Results 61 to 70 of about 1,806,355 (304)

Generic PLM system for SMEs: Application to an equipment manufacturer [PDF]

open access: yes, 2012
For several years, digital engineering has increasingly taken a more important place in the strategic issues of mechanical engineering companies.
BERNARD, Alain   +3 more
core   +8 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

REBRANDING AS A PATTERN OF THE PRODUCT BRAND PROMOTION

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2014
The organizations face to a lack of information for the development and adoption of effective management decisions in modern competitive circumstances.
Эрнст Раисович Сафаргалиев   +1 more
doaj  

Intelligent Human Machine Interface Design for Advanced Product Life Cycle Management Systems

open access: yes, 2009
Designing and implementing an intelligent and user friendly human machine interface for any kind of software or hardware oriented application is always be a challenging task for the designers and developers because it is very difficult to understand the ...
Ahmed, Zeeshan
core   +1 more source

Enhancing service requirements of technical product-service systems [PDF]

open access: yes, 2015
Due to the integration of product and services as a new business model, product reliability and strategies for cost reduction at the early design stage have become important factors for many manufacturing firms.
Estebanez, L. Ruiz   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

STRATEGI PENGEMBANGAN PRODUK DI INDUSTRI MEDIA CETAK DI INDONESIA (Bertahan di tengan Persaingan Media Online

open access: yesBenefit Jurnal Manajemen dan Bisnis, 2014
Understanding the printing press industry position in the product life cycle is very important. This is to determine the right strategy for the printing press in order to be exist and profitable.
Sholahuddin Sholahuddin
doaj  

Religion and Innovation in Europe: Implications for Product Life-Cycle Management [PDF]

open access: yes, 2019
This paper analyzes the relationship between religion and innovation in Europe. To the best knowledge of the authors, no paper has been published about the association of religion with innovation and innovative products and services, at an individual ...
Recio Menéndez, Manuel   +2 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Estimating the Value Added Product Life Cycle [PDF]

open access: yes
This research analyzes factors affecting product and profit life-cycles for new value added products. The methodology used shows how sales and profits evolve and how exogenous factors affecting sales and profits.
Gedikoglu, Haluk   +3 more
core   +1 more source

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