Results 61 to 70 of about 126,766 (289)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Application of Multi-Ribbed Composite Wall Structure in Rural Housing: Seismic, Carbon Emissions, and Cost Analyses

Buildings
Sustainable development is crucial worldwide. Under the Paris Agreement, countries commit to Nationally Determined Contributions (NDCs) assessed every five years. China, a major contributor to global warming, has made significant efforts to reduce carbon
Yanhua Wu, Yue Wang, Haining Wang, Meng Cong, Hong Zhang, Francis Deng Clement, Yiming Xiang, Chun Liu   +7 more
doaj   +1 more source

Consequential LCA and LCC using linear programming: an illustrative example of biorefineries

The International Journal of Life Cycle Assessment, 2019
This paper aims to demonstrate how LCA can be improved by the use of linear programming (LP) (i) to determine the optimal choice between new technologies, (ii) to identify the optimal region for supplying the feedstock, and (iii) to deal with ...
M. Budzinski, M. Sisca, D. Thrän
semanticscholar   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Integration of Cost andWork Breakdown Structures in the Management of Construction Projects [PDF]

, 2020
Scope management allows project managers to react when a project underperforms regarding schedule, budget, and/or quality at the execution stage. Scope management can also minimize project changes and budget omissions, as well as improve the accuracy of ...
Anticona, Aziz, Bartlett, Buchtik, Byrne, Büchmann-Slorup, Camilleri, Cantarelli, Cerezo-Narváez, Cerezo-Narváez, Chrissis, Cooper, Desmond, George, Globerson, González Fernández de Valderrama, Gómez-Senent Martínez, Hair, Hansen, Harrison, Heerkens, Hendrickson, Ho, Hooper, Hughes, Jawad, Kaiser, Kerzner, Khan, Kim, Kline, Kraus, Lee, Liberzon, Lister, Lock, López Paredes, Marsh, Mhetre, Nam, Nayak, Nouban, Park, Pavan, Tabachnick, Taner, Taylor, Teicholz, Thaweejinda, Vahed, Wang, Washington, Yang, Young-Bae   +53 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Spare Parts Cost Management for Long-Term Economic Sustainability: Using Fuzzy Activity Based LCC

Sustainability, 2019
The concept of life cycle sustainability assessment provides an interdisciplinary space to discuss the main challenges in addressing sustainability from a long-term perspective.
Orlando Durán, P. Afonso, P. Durán
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source