Results 51 to 60 of about 86,588 (304)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Agent-Knowledge Logic for Alternative Epistemic Logic

Bulletin of the Section of Logic
Epistemic logic is known as a logic that captures the knowledge and beliefs of agents and has undergone various developments. In this paper, we propose a new logic called agent-knowledge logic by taking the product of individual knowledge structures and
Yuki Nishimura
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Finite sum – product logic

Theory and Applications of Categories, 2001
Summary: In this paper we describe a deductive system for categories with finite products and coproducts, prove decidability of equality of morphisms via cut elimination, and prove a ``Whitman theorem'' for the free such categories over arbitrary base categories.
Cockett, J. R. B., Seely, R. A. G.
openaire   +2 more sources

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Complementary Logic Implementation for Antiferromagnet Field-Effect Transistors

IEEE Journal on Exploratory Solid-State Computational Devices and Circuits, 2018
In this paper, a compact and complementary logic implementation is proposed for antiferromagnet field-effect transistor (AFMFET) devices. The implementation enables a complete set of Boolean operations based on complementary logic as well as majority ...
Chenyun Pan, Azad Naeemi
doaj   +1 more source

Ternary Logic Synthesis with Modified Quine-McCluskey Algorithm

, 2019
Logic synthesis has been increasingly important to accelerate the development of high-level systems. However, in multi-valued logic, logic synthesis methods that can process emerging devices are deficient.
Seokhyeong Kang, Lee, Sung-Yun, Sung-Yun Lee, Sunmean Kim, Kim, Sunmean, Kang, Seokhyeong   +5 more
core   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Static Switching Dynamic Buffer Circuit

Journal of Engineering, 2013
We proposed footless domino logic buffer circuit. It minimizes redundant switching at the dynamic and the output nodes. The proposed circuit avoids propagation of precharge pulse to the output node and allows the dynamic node which saves power ...
A. K. Pandey, R. A. Mishra, R. K. Nagaria   +2 more
doaj   +1 more source

FUZZY-MULTIPLE APPROACH TO RISK ASSESSMENT UNDER THE CONDITIONS OF MANAGEMENT DIGITALIZATION IN ENTERPRISE ACTIVITY

Фінансово-кредитна діяльність: проблеми теорії та практики, 2021
. The success of the enterprise in the market depends on the level of its competitiveness, which, in turn, is determined by the level of competitive advantages of products developed and supplied to the market.Constant updating of the product range by ...
A. Mazaraki , I. Fedulova, Yu. Drozdova, S. Bai   +3 more
doaj   +1 more source