Results 151 to 160 of about 2,783,970 (303)

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

The Ageing, Longevity and Crowding Out Effects on Private and Public Savings: Evidence from Dynamic Panel Analysis [PDF]

open access: yes
Life-cycle theory predicts ageing exerting long-term macroeconomic impacts through the reduction of private savings. Ageing can be brought either through a fall in fertility rates or a rise in longevity. However, empirical research studying macroeconomic
Kam-Ki Tang, Benjamin ShiJie Wong
core  

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

Indeterminacy, intergenerational redistribution, endogenous longevity and human capital accumulation [PDF]

open access: yes
This paper sets up an OLG economy with endogenous life expectancy to study how fiscal policy that redistributes between generations can open the door to sunspot equilibria.
Giam Pietro Cipriani, Miltiadis Makris
core  

The limitations of product longevity

open access: yesProceedings of the 6th Product Lifetimes and the Environment Conference (PLATE2025)
Ingun Grimstad Klepp   +2 more
openaire   +1 more source

Serum enzymes and metabolites related with high production and longevity [PDF]

open access: yesGenetics Selection Evolution, 1976
Kräusslich H   +4 more
openaire   +3 more sources

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

The longevity dividend: Why governments and markets must catch up. [PDF]

open access: yesExp Physiol
Grzesiak N   +6 more
europepmc   +1 more source

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

open access: yesAdvanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh   +8 more
wiley   +1 more source

The Effect of Improvements in Health and Longevity on Optimal Retirement and Saving [PDF]

open access: yes
We develop a life-cycle model of optimal retirement and savings behavior under complete markets where retirement is caused by worsening health in old age. Our model explains the long-run decline in the age of retirement as an income level effect. We show
David E. Bloom   +2 more
core  

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