Results 241 to 250 of about 2,783,970 (303)

Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer

Advanced Science, EarlyView.
The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo, Wei Zhuang, Zean Li, Yiming Lai, Yongyi Ou, Dongquan Li, Shanhe Huang, Tianlong Luo, Jintao Hu, Bingliang Chen, Jianhan Fu, Tao Zhuo, Hankun Jiang, Yin Lu, Hai Huang, Kewei Xu, Shengmeng Peng, Qing Yuan   +17 more
wiley   +1 more source

Grip strength as a systems biomarker of aging: neuromuscular junction constraints and biomarker decoupling in gene therapy. [PDF]

Front Aging
Sewell PE, Jensen C.
europepmc   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Schwann Cell Activity in the Multiple Sclerosis Microenvironment. [PDF]

Cells
Shurin MR, Shurin GV, Doyle CM, Lokshin AE, Wheeler SE.   +4 more
europepmc   +1 more source

Integrating Automated Electrochemistry and High‐Throughput Characterization with Machine Learning to Explore Si─Ge─Sn Thin‐Film Lithium Battery Anodes

Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
A closed‐loop, data‐driven approach facilitates the exploration of high‐performance Si─Ge─Sn alloys as promising fast‐charging battery anodes. Autonomous electrochemical experimentation using a scanning droplet cell is combined with real‐time optimization to efficiently navigate composition space.
Alexey Sanin, Jackson K. Flowers, Tobias H. Piotrowiak, Frederic Felsen, Leon Merker, Alfred Ludwig, Dominic Bresser, Helge Sören Stein   +7 more
wiley   +1 more source

Environmental Quality, Renewable Energy, and Life Expectancy in Gulf Cooperation Council Countries. [PDF]

Int J Environ Res Public Health
Abid I.
europepmc   +1 more source

Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells

Advanced Energy Materials, EarlyView.
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu, Yufei Zhang, Han Zhao, Pooi See Lee, Daniel H.C. Chua   +4 more
wiley   +1 more source

Roles of microRNA in aging and dietary restriction-induced longevity. [PDF]

Front Genet
Fan J, Zhang G, Sun S, Zhang X, Li Y, Liu M, Xu P, Youssef M, Khanzada Z, Zhou Y, Xu Y.   +10 more
europepmc   +1 more source

Temperature-dependent growth and development of Theocolax elegans (Hymenoptera: Pteromalidae) parasitizing Lasioderma serricorne (Coleoptera: Ptinidae). [PDF]

J Insect Sci
Yuan Q, Lü J, Bai C, Guo Y, Du L, Xi J.
europepmc   +1 more source

Growth Performance, Milk Productivity, Productive Longevity, and Milk Composition of Mugalzhar Horses. [PDF]

Animals (Basel)
Toishimanov M, Alikhanov O, Aubakirov K, Karibayeva D, Kargaeva M, Sapakhova Z, Begaliyeva D, Kanat R, Tugunova Y, Daurov D, Daurova A, Zhambakin K, Shamekova M, Baimukanov D.   +13 more
europepmc   +1 more source