Results 41 to 50 of about 6,354,822 (301)

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie   +4 more
wiley   +1 more source

Stochastic model for product supplier selection [PDF]

open access: yesBIO Web of Conferences
The aim of the article is to develop a model of rational choice of technology and equipment supplier under conditions of external environment uncertainty. The technical and economic requirements of the customer are considered as operational, i.e.
Dokukin Alexander   +3 more
doaj   +1 more source

Multi-Characteristic Product Price Research Based on GSADF-BP Model

open access: yesIEEE Access, 2021
According to hedonic price theory, people’s demand for product is based on the product characteristic. Pu’er tea is geographical indicator product of Yunnan province, which has edible, medicinal, drinking, investment and cultural value.
Mingxin Ji   +3 more
doaj   +1 more source

Towards Product Lining Model-Driven Development Code Generators [PDF]

open access: yes, 2015
A code generator systematically transforms compact models to detailed code. Today, code generation is regarded as an integral part of model-driven development (MDD).
Roth, Alexander, Rumpe, Bernhard
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Neuroprotective Effects of Albizia lebbeck (L.) Benth. Leaf Extract against Glutamate-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Microglial Cells

open access: yesPharmaceuticals, 2023
Endoplasmic reticulum (ER) stress caused by excessive glutamate in the central nervous system leads to neurodegeneration. Albizia lebbeck (L.) Benth. has been reported to possess neuroprotective properties.
Onuma Phoraksa   +8 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Hipsters on Networks: How a Small Group of Individuals Can Lead to an Anti-Establishment Majority [PDF]

open access: yes, 2018
The spread of opinions, memes, diseases, and "alternative facts" in a population depends both on the details of the spreading process and on the structure of the social and communication networks on which they spread.
Juul, Jonas S., Porter, Mason A.
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

open access: yesSignal Transduction and Targeted Therapy, 2021
To discover new drugs to combat COVID-19, an understanding of the molecular basis of SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of cathepsin L (CTSL) in patients with COVID-19.
Miao-Miao Zhao   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy