Results 41 to 50 of about 116,392 (265)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Oil & Gas Science and Technology, 2019 This article discusses the issue of assessment of the quality of petroleum pipeline preparation for light oil product transportation. The need to implement appropriate measures is conditioned by the requirement to maintain the quality of oil products ...
Sunagatullin Rustam +3 more
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You-qi chuyun, 2020 Oil pipeline leakage will cause direct economic losses and even adversely affect the surrounding environment and residents along the pipeline. It is crucial to be aware of the seepage, surface diffusion and evaporation of leaked oil in the surrounding ...
Shengli LIU, Yongtu LIANG, Xiao WANG
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Pipelined Filter Combination in Product Personalization
, 2003 In many cases, standard of-the-shelf products—i.e., products without individual customization— do not meet all customer requirements. Therefore, for instance, the automotive industry produces vehicles with personalized characteristics. Can this customization be further improved w.r.t. production time, especially in B2P relations?
Renneberg, Volker, Borghoff, Uwe M.
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The behavior of a co-flow structure to screen projects in a product pipeline
GEPROS: Gestão da Produção, Operações e Sistemas, 2016 In many situations, System Dynamics modelers have to capture attributes of items tracked in an aging chain by means of a co-flow. This study presents an application of co-flows in aging chains: A co-flow that enables the process of screening, i.e.
Paulo S. Figueiredo, Elisabeth Loiola
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Shiyou huagong gaodeng xuexiao xuebaoDuring the shutdown period of the J-Y refined oil product pipeline, there is a significant difference between the temperature of the transported oil and the outside soil temperature, which leads to a pressure drop in the pipeline after the shutdown. When
Yanchao WEI +6 more
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