Results 61 to 70 of about 16,636,722 (292)

Production and Quality Management for SDGs

, 2022
AbstractIndustry has undertaken mass production and consumed resources to optimize only economic efficiency. Most products are discarded or disposed at the end of their lifetimes. Therefore, most companies should design and manage their production system for sustainability. One of the most important factors to develop a sustainable production system is
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Influence of the genotype of the hen (Gallus gallus domesticus) on main parameters of egg quality, chemical composition of the eggs under uniform environmental conditions

Poultry Science
: The objective of this study was to identify and compare the quality characteristics and concentrations of various compounds in eggs from several pure breeds and lines of hens reared under the same environmental conditions and fed a commercial feed.
M. Hejdysz, S. Nowaczewski, K. Perz, T. Szablewski, K. Stuper-Szablewska, R. Cegielska-Radziejewska, Ł. Tomczyk, A. Przybylska-Balcerek, M. Buśko, S.A. Kaczmarek, P. Ślósarz   +10 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Polycomb Group Proteins in Drosophila melanogaster

Biology
The development of multicellular organisms relies on the precise establishment and stable inheritance of cell type-specific transcriptional programs without changes to the underlying DNA sequence.
Fei Gao, Zicheng Li, Xiaoping Yu, Sunjie Chen, Chengcheng Ye   +4 more
doaj   +1 more source

PRODUCT QUALITY MANAGEMENT IN CLIMATE-SMART AGRICULTURE WITH THE HELP OF CORPORATE INFORMATION SYSTEMS BASED ON MACHINE LEARNING [PDF]

Proceedings on Engineering Sciences
We dwelt on the directions of product quality management in the conditions of climate-smart agriculture with the application of corporate information systems based on machine learning. The revealed aspects are used with different results within different
Dinara A. Osmonalieva , Chinara R. Kulueva , Ibrokhimbek D. Nasirkhodjaev , Kirill Y. Tikhomirov , Arsen A. Petrosyan   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Electrical Properties of Engine Oils—Comparison of Electrical Parameters with Physicochemical Characteristics

Energies
The increasing demand for the real-time monitoring of engine oil quality has driven the development of novel diagnostic methods. Traditional techniques primarily rely on physicochemical assessments, which, while effective, are often time consuming and ...
Artur Wolak, Ryszard Żywica
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source