Results 81 to 90 of about 16,636,722 (292)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Dimensions of perceived product quality – understanding the consumer’s view [PDF]
, 2009 Objectives. We identify core product quality components from the consumers’ perspective and construct a psychometrically sound instrument for their assessment within different purchasing contexts. Methods.
Tumasjan, Andranik +3 more
core +1 more source
Design and management of manufacturing systems for production quality
CIRP Annals, 2014 Manufacturing companies are continuously facing the challenge of operating their manufacturing processes and systems in order to deliver the required production rates of high quality products, while minimizing the use of resources. Production quality is proposed in this paper as a new paradigm aiming at going beyond traditional six-sigma approaches ...
Colledani +13 more
openaire +5 more sources
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Mineral intrusion in Kansas surface waters : a technical report [1979]
, 1979 On cover: Kansas water quality management plan, 1978.; "Prepared by the Kansas Water Resources Board for the Water Quality Management Section."; Includes bibliographical references.Report covers the locating and defining of areas of natural mineral ...
Hargadine, Gerald D.
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Analysis of health warning signs on alcoholic beverage packaging using the eye-tracking method
Engineering Management in Production and ServicesProducers must mark packaging with various warning signs, including the harm of alcohol consumption. The most popular warnings inform about the required consumer age (e.g., “alcohol only for adults”), consequences of drunk driving (e.g., “don’t drink and
Cholewa-Wójcik Agnieszka +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source