Results 111 to 120 of about 12,708 (270)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

La traducció de productes d'animació per a doblatge en català [PDF]

open access: yes, 2009
Traduir productes audiovisuals d'animació no és una pràctica uniforme a la qual es puguin atribuir una sèrie de característiques exclusives, sinó que l'etiqueta «animació» fa referència únicament a la tècnica de creació feta servir i, en conseqüència ...
Matamala, Anna
core  

L’emulació és la forma d’adulació més sincera: Videojocs retro, distribució de ROM i drets d’autor

open access: yesIDP, 2012
Internet ha permès als creadors de jocs amateurs col·laborar en projectes independentment de la seva situació geogràfica. L'èxit de productes com Minecraft, i fins i tot CounterStrike, demostra que els desenvolupadors «independents» poden crear productes
Benjamin Farrand
doaj  

Productivity and production

open access: yesCalifornia Agriculture, 1986
California Agriculture - All ...
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Design and Evaluation of an Osteogenesis-on-a-Chip Microfluidic Device Incorporating 3D Cell Culture. [PDF]

open access: yesFront Bioeng Biotechnol, 2020
Bahmaee H   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Real-World Evidence Study on the Long-Term Safety of Everolimus in Patients With Tuberous Sclerosis Complex: Final Analysis Results. [PDF]

open access: yesFront Pharmacol, 2022
Ruiz-Falcó Rojas ML   +8 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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