Results 61 to 70 of about 12,708 (270)

Cytotoxic Agents of the Crinane Series of Amaryllidaceae Alkaloids

open access: yesNatural Product Communications, 2012
In the alkaloid galanthamine, the plant family Amaryllidaceae has endowed the pharmaceutical community with a potent and selective inhibitor of the enzyme acetylcholinestersae (AChE), of prominence in the chemotherapeutic approach towards motor neuron ...
Jerald J. Nair   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

No malbaratis: llet i productes lactis frescos [PDF]

open access: yes, 2016
Malbaratament d'aliments; Productes lactis; Seguretat alimentàriaDesperdicio de alimentos; Productos lácteos; Seguridad alimentariaFood Wastefulness; Dairy Products; Food safetyCartell que ofereix consells als consumidors per no malbaratar aliments ...

core  

Recuperen productes bioactius del paleolític amb possibles aplicacions per a la salut humana [PDF]

open access: yes, 2023
La revolució neolítica va significar un canvi radical en l'estil de vida dels nostres avantpassats, que va afectar tots els camps de la cultura i la tècnica, inclosa l'alimentació.
Bueno i Torrens, David, 1965-
core   +1 more source

Cytotoxic Agents of the Crinane Series of Amaryllidaceae Alkaloids

open access: yesNatural Product Communications, 2013
In the alkaloid galanthamine, the plant family Amaryllidaceae has endowed the pharmaceutical community with a potent and selective inhibitor of the enzyme acetylcholinestersae (AChE), of prominence in the chemotherapeutic approach towards motor neuron ...
Jerald J. Nair   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Productes alimentosos. Curs 2008-2009 [PDF]

open access: yes, 2008
Pla docent de l'assignatura Productes alimentosos de l'Ensenyament de Ciència i Tecnologia dels Aliments. Curs acadèmic 2008-2009.
Universitat de Barcelona. Facultat de Farmàcia
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Dissenyen un catalitzador per obtenir productes químics a partir de gasos d’efecte hivernacle [PDF]

open access: yes
Tres investigadors del grup de recerca d'Innovació en Materials i Enginyeria Molecular - Biomaterials per a Teràpies Regeneratives (IMEM-BRT) de la UPC, en col·laboració amb el doctor Pau Turón, de l'empresa B.Braun Surgical, han creat un catalitzador ...

core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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