Results 71 to 80 of about 3,105,445 (332)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Developing capabilities in the seed industry: which direction to follow? [PDF]
, 2014 Since the 1990s, many developing country policy makers have assumed that plant genetic engineering represents the only technological frontier in seed innovation; that it has been the leading technology for improving seeds and agricultural performance in ...
Marin, Anabel +2 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A stoichiometric reaction scheme for Saccharothrix algeriensis growth and thiolutin production [PDF]
, 2010 A new bacterial species, Saccharothrix algeriensis NRRL B-24137, was isolated in 1992 in the Sahara desert. This filamentous bacterium is able to produce dithiolopyrrolones, molecules presenting antibacterial, antifungal, and anticancer properties.
Brandam, Cédric +3 more
core +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Engineering nature for gaseous hydrocarbon production
Microbial Cell Factories, 2020 The development of sustainable routes to the bio-manufacture of gaseous hydrocarbons will contribute widely to future energy needs. Their realisation would contribute towards minimising over-reliance on fossil fuels, improving air quality, reducing ...
Mohamed Amer +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Engineering visualization utilizing advanced animation [PDF]
Engineering visualization is the use of computer graphics to depict engineering analysis and simulation in visual form from project planning through documentation.
Robinson, Thomas L., Jr. +1 more
core +1 more source
Flexible PCL tube scaffolds by winding of micro-extruded filaments [PDF]
, 2011 An important requirement for tissue engineering scaffolds is matching of the functional me-chanical properties to their natural tissue counterpart. Specifically for arteries this comprises the elastic re-sponse of the vessel wall to blood pressure. Human
Cardon, Ludwig +2 more
core +1 more source
Information About Cost of Goods Produced and its Usefulness for Production Engineers – A Case of SME
Management Systems in Production Engineering, 2017 The article stresses the consequences of simplifications implemented in the measurement process of goods produced that are of crucial importance to production engineers in SME. The authors show the variety of possibilities that might be used by financial
Maruszewska Ewa Wanda +2 more
doaj +1 more source