Results 81 to 90 of about 3,105,445 (332)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Engineering verification of the biomass production chamber [PDF]

open access: yes
The requirements for life support systems, both biological and physical-chemical, for long-term human attended space missions are under serious study throughout NASA.
Jones, J. D.   +3 more
core   +1 more source

Final results from the EU project AVATAR: aerodynamic modelling of 10 MW wind turbines [PDF]

open access: yes, 2018
This paper presents final results from the EU project AVATAR in which aerodynamic models are improved and validated for wind turbines on a scale of 10 MW and more.
Barakos, G.   +16 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Influence of Physical Fatigue on Work on a Production Line

open access: yesActa Technologica Agriculturae, 2017
The purpose of this study is to determine the factors having impacts on the physical fatigue of employees and to analyse its influence on work on a production line.
Kołodziej Sabina, Ligarski Mariusz J.
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Aspects of sustainability and design engineering for the production of interconnected smart food packaging [PDF]

open access: yes, 2019
In the present work, the problem of food wastage and the concept of sustainability are studied. An analysis of Life Cycle Assessment as a tool and of the innovative concept of Cradle to Cradle is also carried out, together with an exhaustive comparison
Aguayo-González, Francisco   +4 more
core   +2 more sources

Worker assignment models for hiring people with disabilities in service organizations

open access: yesCLEI Electronic Journal
A diverse workforce is one of the most important assets for modern organizations. In this sense, the integration of workers with disabilities is both an opportunity in terms of staff diversity and of corporate social responsibility, and, in many cases ...
Héctor Cancela   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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