Results 151 to 160 of about 6,552,071 (296)

Is the Glass Half-Empty or Half Full? An Analysis of Agricultural Production Trends in Zambia [PDF]

One objective of this paper is to examine the trends and changes in crop production before and after the implementation of the partial market liberalization policies starting in the early 1990s.
Jayne, Thomas S., Zulu, Ballard, Negassa, Asfaw, Nijhoff, Jan J.   +3 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Metaheuristic-driven automatic ARIMA order selection using spider monkey optimization for agricultural production forecasting. [PDF]

MethodsX
Kumar A, H RPC, P FK, Rathod S, Shankar SV, Ray M, B SAS, Patil S, Mazumder C, Mishra SK, Lavanya V, Misra AK, Choudhary VK.   +12 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Data-driven forecasting of Flu, RSV, and COVID-19 related outcomes in the United States and Canada via Hankel dynamic mode decomposition. [PDF]

PLoS One
Redman WT, Mullany LC.
europepmc   +1 more source

The Production and Consumption of Commercial Real Estate Market Forecasts [PDF]

Whilst the vast majority of the research on property market forecasting has concentrated on statistical methods of forecasting future rents, this report investigates the process of property market forecast production with particular reference to the ...
Pat McAllister, Paul Gallimore
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Very short-term production prediction for photovoltaic plants using Temporal Convolutional Networks. [PDF]

PLoS One
Samaras L, García-Barriocanal E, Sicilia MA, García LG.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Horizon-Dependent Solar Irradiance Forecasting with Boosted Trees, and Seasonal Baselines Based on Measurements in Sudan. [PDF]

Sensors (Basel)
Mohamed EIE, Akgun D, Ashri S, Khachan A, Elsheikh EAA, Aksoy Tirmikci C.   +5 more
europepmc   +1 more source