Results 161 to 170 of about 6,191,019 (284)

A Review of Novel Antioxidant Ergothioneine: Biosynthesis Pathways, Production, Function and Food Applications. [PDF]

Foods
Zhang H, Liu Z, Wang Z, Lei Z, Jia Y, Chen W, Shi R, Wang C.   +7 more
europepmc   +1 more source

Soluble immune checkpoints in cancer: production, function and biological significance. [PDF]

J Immunother Cancer, 2018
Gu D, Ao X, Yang Y, Chen Z, Xu X.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Measuring financial sector efficiency in China: A study based on an enhanced neoclassical production function. [PDF]

PLoS One
Zheng C, Shan Y.
europepmc   +1 more source

The marginal benefits of healthcare spending in the Netherlands: Estimating cost-effectiveness thresholds using a translog production function. [PDF]

Health Econ, 2019
Stadhouders N, Koolman X, van Dijk C, Jeurissen P, Adang E.   +4 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The production, function, and clinical applications of IL-33 in type 2 inflammation-related respiratory diseases. [PDF]

Front Immunol
Gu S, Wang R, Zhang W, Wen C, Chen C, Liu S, Lei Q, Zhang P, Zeng S.   +8 more
europepmc   +1 more source

Africa Rising, a Narrative for Life Expectancy Gains? Evidence from a Health Production Function. [PDF]

Ann Glob Health, 2019
Salami D, Shaaban AN, Oliveira Martins MDR.   +2 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Multifactorial Causes and Consequences of TLSP Production, Function, and Release in the Asthmatic Airway. [PDF]

Biomolecules
Brister DL, Omer H, Whetstone CE, Ranjbar M, Gauvreau GM.   +4 more
europepmc   +1 more source