Results 191 to 200 of about 2,293,195 (264)

Safety evaluation of an extension of use of the food enzyme triacylglycerol lipase from the genetically modified <i>Aspergillus oryzae</i> strain NZYM-FL. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Rosell AF, Cavanna D, Liu Y.   +15 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Nutrition, Cell Signalling, Mitochondrial Function, and Chronic Non-Communicable Disease. [PDF]

Int J Mol Sci
Phillips R.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Gut-brain axis and post-operative cognitive dysfunction: A multifactorial perspective on microbiota, inflammation, and cognitive health. [PDF]

World J Gastrointest Pharmacol Ther
Joshi R, Gupta N, Gupta A, Khanna P, Verma N, Kaur S.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Beyond the neuron: Exosomes as intercellular modulators of mitochondrial networks in the pathogenesis and treatment of Alzheimer's disease. [PDF]

Alzheimers Dement
Xing L, Liu A, Gao W, Li J, Yao M, Song J, Duan P, Li H.   +7 more
europepmc   +1 more source

Hydroxyl radical production in liquid water by laser cavitation. [PDF]

Sci Rep
Zhou X, Gu J.
europepmc   +1 more source

Specific Ion Chemistry at the Air-Water Interface of Nitrite/Nitrate-Containing Droplets. [PDF]

Environ Sci Technol
Carreira Mendes Da Silva Y, Angelaki M, Gandolfo A, Donaldson DJ, George C.   +4 more
europepmc   +1 more source

Pathogenic role of mitochondrial DNA mutations in heart failure: clinical features, mechanisms, and therapeutic prospects. [PDF]

Front Cardiovasc Med
Ni M, Zheng A, Zheng H, Jia W, Wang Y, Peng Y, Yao C, Wei Y, Wang X, Kang S.   +9 more
europepmc   +1 more source