Results 201 to 210 of about 20,186,890 (357)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Real time estimation of potential output and output gap for theeuro-area: comparing production function with unobserved componentsand SVAR approaches

We develop a new version of the production function (PF) approach usually used for estimating the output gap of the euro area. Our version does not call for any (often imprecise) measure of the capital stock and improves the estimation of the trend total
Monperrus-Veroni, Paola, Lemoine, Matthieu, Mazzi, Gian Luigi, Reynes, Frédéric   +3 more
core   +1 more source

Production function, econometric approach

, 1987
Bu yazının amacı üretim fonksiyonunun ampirik olarak belirlenmesi açısından geçerli önemli noktaları vurgulamaktır.The aim of this paper is to discuss those points that are relevant to the empirical determination of the production ...

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Multifactorial Causes and Consequences of TLSP Production, Function, and Release in the Asthmatic Airway. [PDF]

Biomolecules
Brister DL, Omer H, Whetstone CE, Ranjbar M, Gauvreau GM.   +4 more
europepmc   +1 more source

Estimation of a Neonatal Health Production Function for Iran: Secondary Analysis of Iran's Multiple Indicator Demographic and Health Survey 2010. [PDF]

Iran J Public Health, 2019
Amini-Rarani M, Rashidian A, Bayati M, Khedmati Morasae E.   +3 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Determinants of meat and milk production of Awassi sheep in Syria: A Cobb-Douglas production function estimation approach. [PDF]

Heliyon
AlFraj NK.
europepmc   +1 more source

Parenting Skills and Early Childhood Development: Production Function Estimates from Longitudinal Data. [PDF]

Rev Econ Househ, 2019
Jenkins JM, Handa S.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Technical productivity analysis for cement industry at firm level [PDF]

This paper analyses the energy use in the manufacture of cement in India during 1992-2005. Cement manufacturing requires large amounts of various energy inputs. The most common types of energy carriers used are coal, electricity, natural gas and fuel oil.
B. Sudhakara Reddy, Binaykumar Ray
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