Results 91 to 100 of about 13,118,916 (332)
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Research of large chemical production line simulation technology
, 2016 The aim of simulation technique for production line is to find out the most feasible scheme which designers made for the project. Simulation technique can verify the actual effect of the project from the schemes. Combined with the actual production mode,
Bai XL(白鑫林) +4 more
core
EngThis study investigates the effect of stabilizing axial load transfer to the bit on mechanical-specific energy during horizontal well drilling. To analyze drilling regimes, field data on WOB, ROP, RPM, TOB, and MSE were used and processed using z-score ...
George Buslaev +2 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Novel Gesture-Based Robot Programming Approach with the Ability of Code Reuse
MachinesNowadays, there is a worldwide demand to create new, simpler, and more intuitive methods for the manual programming of industrial robots. Gestures can allow the operator to interact with the robot more simply and naturally, as gestures are used in ...
Vladyslav Andrusyshyn +3 more
doaj +1 more source
Machine learning in optimization of nonwoven fabric bending rigidity in spunlace production line. [PDF]
Sci Rep, 2023 Sadeghi MR +2 more
europepmc +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Dynamic maintenance priority of a real-world machining line
, 2016 To support the shop-floor operators, decision support systems (DSS) are becoming more and more vital to the success of manufacturing systems in industry today.
Holm, Magnus +5 more
core +1 more source