Results 81 to 90 of about 13,645,076 (329)

Modernização industrial em indústria de mão-de-obra: automação, informatização e inovações organizacionais na indústria do vestuário

open access: yesProduction, 1991
Através de pesquisa de campo em empresas lideres do vestuário no Rio de Janeiro e em São Paulo buscou-se explicitar as motivações básicas para a informatização e a automação da produção no setor e evidenciar a lógica na introdução das inovações ...
Silvio Roberto Souza Tavares
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Sustainable Production Management in Circular Economy Supply Chains [PDF]

open access: yesInternational Journal of Industrial Engineering and Management
The transition to circular economy (CE) principles represents a critical challenge for sustain- able industrial development. This study investigates the implementation and effectiveness of sustainable production management strategies within CE-based ...
Zulki Zulkifli Noor
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Analyzing the production management of nomadic livestock products (Case study: Nomads of Hamuleh clan, Bakhtiari tribe) [PDF]

open access: yesDānishhā-yi būmī-i Īrān
According to the results of the last socio-economic census of the nomadic nomads (year 1400), the number of 1,186,398 nomadic people in the form of 212,772 households annually brings about 9 million livestock units in excess of the need to the market ...
ali mohebi, saeedeh nateghi
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Complexidade do produto e volume de produção como determinantes da estratégia de desenvolvimento de fornecedores automotivos Product complexity and production volumes as determining factors of small and medium-sized automotive supplier development strategies

open access: yesGestão & Produção, 2005
Este artigo apresenta as diferentes estratégias de desenvolvimento de pequenos e médios fornecedores de três grupos de grandes empresas automotivas localizados no Rio Grande do Sul. Conforme constatado, esses três grupos de empresas apresentam diferentes
Giancarlo Medeiros Pereira   +1 more
doaj   +1 more source

Advances in Production Management Systems. Innovative and Knowledge-Based Production Management in a Global-Local World

open access: yesIFIP Advances in Information and Communication Technology, 2014
Knowledge management.- Creative enterprise.- Quality management.- Design tools.- System engineering.- PLM.- Ontology.- Decision support system.- Collaboration maturity.- Business intelligence.- Enterprise 2.0.- Scheduling.- Optimization.- Production ...
B. Grabot   +4 more
semanticscholar   +1 more source

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