Results 51 to 60 of about 10,607,986 (289)

Integrated production planning and quality control for linear production systems under uncertainties of cycle time and finished product quality

open access: yesInternational Journal of Production Research, 2019
This work considers serial production systems with several process steps and a possible quality control at final step. It deals with the problem of optimising planned lead time when the real lead time for each process is stochastic and the finished ...
O. Ben-Ammar, B. Bettayeb, A. Dolgui
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Joint Decision-Making Model for Production Planning and Maintenance of Fully Mechanized Mining Equipment

open access: yesIEEE Access, 2021
With the development of complex and intelligent sizeable mechanical equipment, the conflict between maintenance and production is becoming increasingly severe, restricting coal mine enterprises’ production and development.
Xiangang Cao, Pengfei Li, Yong Duan
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Designing a Dynamic and Sustainable Cellular Manufacturing System by Considering the Amount of Energy Consumption and Manpower in Production Planning [PDF]

open access: yesمجله مدل سازی در مهندسی
The design and planning of cellular Manufacturing systems in most classical models is based on minimizing production costs or increasing producers' profits.
Nader Ghanei   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Plan maestro de producción basado en programación lineal entera para una empresa de productos químicos || Master Production Scheduling Based on Integer Linear Programming for a Chemical Company

open access: yesRevista de Métodos Cuantitativos para la Economía y la Empresa, 2017
En este trabajo se propone un modelo de programación lineal entera para planificar la producción de un conjunto de artículos finales con demanda independiente.
Reyes Zotelo, Yunuem   +3 more
doaj  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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