Results 71 to 80 of about 2,279,555 (304)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Gestão & Produção, 1995 O artigo trata da determinação de uma política ótima de decisão para um problema de planejamento da produção com restrições de estoque e produção. O horizonte de planejamento é finito, aproximadamente de 1 a 2 anos, com período de discretização mensal ...
Oscar S. Silva Filho +3 more
doaj +1 more source
Mayoral views on housing production: do planning goals match reality? [PDF]
, 2019 Mayoral Views on Housing Production: Do Planning Goals Match Reality? evaluates mayoral priorities relative to actual need. Based on our analysis, even the most ambitious mayors are not prioritizing sufficient development necessary to meet the demand for
Einstein, Katherine Levine +1 more
core
A heuristic approach for big bucket multi-level production planning problems [PDF]
, 2009 Multi-level production planning problems in which multiple items compete for the same resources frequently occur in practice, yet remain daunting in their difficulty to solve. In this paper, we propose a heuristic framework that can generate high quality
Akartunali, Kerem, Miller, Andrew
core +3 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Gestão & Produção, 2000 The paper examines the current state of Production Planning and Control (PPC), identifies some technical and systems changes that have occurred over recent years and links these with the requirements being placed on companies by the market.
Maurice Bonney
doaj +1 more source
Hard, soft or lean? Planning on medium size construction projects [PDF]
, 1999 In a paper presented to the 11th Annual ARCOM Conference, Johansen examined the way that managers and planners in medium sized construction projects plan in a flexible manner.
Greenwood, David, Johansen, Eric
core
Of good plants and useless weeds: planning as a spatial technology of the gardening state [PDF]
, 2017 The article deploys Bauman’s metaphor of the ‘gardening’ state to consider the imbrication of planning and the dark side of modernity. It interrogates the public production and defence of urban spaces suitable for people deemed to have value.
Kamete, Amin Y.
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source