Results 71 to 80 of about 379,677 (312)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

An Intelligent Digital Twin Streamlines Production Planning in the Context of Custom 3D Workpieces for Powder Coating

IEEE Access
An Intelligent Digital Twin (IDT) was created to analyze 3D-CAD models for optimizing individual production plans in the context of powder coating.
Cedric Kiener, Steffen Schwarzer, Simon Zimmermann   +2 more
doaj   +1 more source

Planejamento agregado da produção ótimo com limite mínimo de estoque influenciado pelas incertezas de demanda Optimal aggregate production planning with minimum inventory limit affected by demand uncertainties

Gestão & Produção, 1995
O artigo trata da determinação de uma política ótima de decisão para um problema de planejamento da produção com restrições de estoque e produção. O horizonte de planejamento é finito, aproximadamente de 1 a 2 anos, com período de discretização mensal ...
Oscar S. Silva Filho, Marcius F. H. Carvalho, Moisés M. Henrique, Carlos A. Fernandes   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Compartilhamento da informação como elemento de coordenação da produção em cadeia de suprimento Information sharing as an element of production coordination in supply chains

Gestão & Produção, 2005
Este artigo estuda o planejamento da produção de uma cadeia de suprimento sob três cenários distintos de gestão e compartilhamento da informação, por meio de um modelo de otimização. No primeiro cenário são utilizadas somente as informações locais.
Pythágoras Grangeiro Furtado, Marcius Fabius Henriques de Carvalho   +1 more
doaj   +1 more source

Production planning in 3D printing factories

International Journal of Production Management and Engineering, 2020
Production planning in 3D printing factories brings new challenges among which the scheduling of parts to be produced stands out. A main issue is to increase the efficiency of the plant and 3D printers productivity.
J. De Antón, J. Senovilla, J.M. González, F. Acebes   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Evolvable production systems and impacts on production planning

, 2011
Production planning and control strategies have been changing in line with the constant change on product and customer requirements, under the light of technological and scientific advancements.
Mauro Onori, Akillioglu, Hakan,, Onori, Mauro,, Hakan Akillioglu   +3 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Production planning and control in major industries in Korea

, 2018
This paper presents an extensive survey on many application research activities in production planning, scheduling and control in major industries in Korea.
Hong, YS, Seong, D
core   +1 more source