Results 81 to 90 of about 2,279,555 (304)

Compartilhamento da informação como elemento de coordenação da produção em cadeia de suprimento Information sharing as an element of production coordination in supply chains

open access: yesGestão & Produção, 2005
Este artigo estuda o planejamento da produção de uma cadeia de suprimento sob três cenários distintos de gestão e compartilhamento da informação, por meio de um modelo de otimização. No primeiro cenário são utilizadas somente as informações locais.
Pythágoras Grangeiro Furtado   +1 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Development of a Simulation Model to Improve the Functioning of Production Processes Using the FlexSim Tool

open access: yesApplied Sciences
One of the goals of Industry 4.0 is to increase the transparency of the value chain through modern tools in production processes. This article aims to discuss the possibility of increasing the efficiency of a production system by modernizing it with the ...
Wojciech Lewicki   +2 more
doaj   +1 more source

Reference Models for Production Planning and Control Systems: A Bibliometric Analysis and Future Perspectives [PDF]

open access: yes, 2018
The activity of modeling business processes is still not a common practice among organizations which contributes to increase the cost and time of systems deployment, improvement projects and educational software, due to the need to develop new models ...
Entringer, T. C. (Tulio)   +3 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Wind Turbines In The Landscape: Final Report & Script [PDF]

open access: yes, 1994
The aim of this project was to produce a video film where the visual impact issues associated with current UK wind farms are addressed. The video is targeted to an audience of planners, planning committee members, planning consultants, environmental ...
Cook, T, Robotham, AJ
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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