Results 241 to 250 of about 4,393,221 (308)

Characterization of <i>Nigella sativa</i> Meal (NSM) and the Effects on <i>In Vitro</i> Rumen Fermentation and Degradability. [PDF]

Animals (Basel)
Juandita KN, Ramdani D, Hernaman I, Chaudhry AS, Sukarman, Sarwono KA.   +5 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Extracellular superoxide production by <i>Porites</i> species provides insight into controls on coral physiology. [PDF]

PNAS Nexus
Grabb KC, Herrera S, Roberson LM, Sánchez-García M, Page HN, Hansel CM.   +5 more
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Transforming Small Ruminant Productivity Through a Farm Service Delivery Model: Evidence from a Pilot Study in Saudi Arabia. [PDF]

Animals (Basel)
Swaminathan M, Aldayood K, Tibbo M, Ghosh K, Shaikhi A, Haddad N.   +5 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

LAG3 constrains anti-parasitic response by effector CD4⁺ T-cell in early Echinococcus multilocularis-infected mice. [PDF]

Parasit Vectors
Ainiwaer A, Li D, Liu W, Deng B, Li Y, Xiao W, Sun S, Gao Y, Tang N, Ge C, Li J, Wang H, Zhang C.   +12 more
europepmc   +1 more source

Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization. [PDF]

J Basic Microbiol
Yang C, Yajing Y, Housheng H.
europepmc   +1 more source

Behavioral and economic drivers of antimicrobial use in commercial poultry farms in Bangladesh: A qualitative study. [PDF]

One Health
Chowdhury NN, Khan AKMD, Khan MA, Noman MZI, Islam M, Al-Mamun A, Hasan MM, Choudhury SD, Hassan MM, Forwood JK, Shirin T, Islam A.   +11 more
europepmc   +1 more source