Results 51 to 60 of about 1,415,684 (317)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Product Rules in Semidefinite Programming [PDF]

, 2007
In recent years we witness the proliferation of semidefinite programming bounds in combinatorial optimization [1,5,8], quantum computing [9,2,3,6,4] and even in complexity theory [7]. Examples to such bounds include the semidefinite relaxation for the maximal cut problem [5], and the quantum value of multi-prover interactive games [3,4].
Rajat Mittal 0001, Mario Szegedy
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

OPTIMIZATION OF THE PRODUCTION PROGRAM FOR MEDICAL CORK MANUFACTURERS USING MATHEMATICAL PROGRAMMING AND SIMULATION METHODS

Russian Journal of Economics and Law, 2011
For the companies that manufacture medical cork, one of the key elements of effective action is the optimal management of production program. Specificity of planning the production program of these enterprises, which is associated with both internal and ...
A. A. Kushner
doaj  

Annual Grass Silage: A Productive and Cost-Effective Strategy for Ruminant Nutrition

Advances in Agriculture
This study was conducted to evaluate the agronomic performance, fermentation characteristics, cost analysis, and financial returns of silage produced from annual forage crops.
Felipe Pontes Teixeira das Chagas, Ana Beatriz Graciano da Costa, Stela Antas Urbano, Juliana Caroline Santos Santana, Anne Carolinne Rodrigues Linhares da Silva, Patrick Bezerra Fernandes, Kyvia Pontes Teixeira das Chagas, Flávio Pereira da Mota Silveira, João Virgínio Emerenciano Neto   +8 more
doaj   +1 more source

Corporate Sustainability and Wealth Distribution: Evidence from Brazil’s Corporate Sustainability Index

Administrative Sciences
The growing demand for sustainable business practices has led to the development of corporate sustainability assessment tools, with environmental, social, and governance (ESG) indicators becoming central to non-financial performance evaluation.
Paulo A. Lozano, Feni Agostinho, Arno P. Clasen, Cecília M. V. B. Almeida, Biagio F. Giannetti   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

ESSENCE OF MANAGEMENT OF AN ENTERPRISE PRODUCTION PROGRAM AND THE ROLE OF ANALYSIS IN THIS PROCESS

Russian Journal of Economics and Law, 2012
The article presents critical investigation of the existing approaches to the production program management and proposes the author's interpretation of the mentioned category.
O. V. Askanova
doaj  

Analysis of Strategies to Combat Cargo Theft and Robbery in Peripheral Communities of São Paulo, Brazil, Using a Paraconsistent Expert System

Logistics
Background: Cargo theft represents a persistent challenge to last-mile logistics in the peripheral regions of São Paulo, Brazil, compromising transportation security and increasing operational costs.
Kennya Vieira Queiroz, Jair Minoro Abe, João Gilberto Mendes dos Reis, Miguel Renon   +3 more
doaj   +1 more source