Results 51 to 60 of about 4,393,221 (308)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Computer program determines inventory size [PDF]

, 1966
FORTRAN 4 computer program calculates optimum size of a small inventory of relatively complex or expensive items. This program can be used in situations where the initial cost of purchase is large or when there is a need for a balanced inventory on a ...
Kaspar, H.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Study on Program Production of Liputan Cilik Daai Tv

Humaniora, 2016
Research goal of this study was to know the program production process of Liputan Cilik DAAI TV in Jakarta. Method used in this study was a qualitative method with analysis participatory observation and in-depth interviews with the crew involved in this
Mariana Mariana, Heribertus Sunu Budihardjo   +1 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Product Rules in Semidefinite Programming [PDF]

, 2007
In recent years we witness the proliferation of semidefinite programming bounds in combinatorial optimization [1,5,8], quantum computing [9,2,3,6,4] and even in complexity theory [7]. Examples to such bounds include the semidefinite relaxation for the maximal cut problem [5], and the quantum value of multi-prover interactive games [3,4].
Rajat Mittal 0001, Mario Szegedy
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

OPTIMIZATION OF THE PRODUCTION PROGRAM FOR MEDICAL CORK MANUFACTURERS USING MATHEMATICAL PROGRAMMING AND SIMULATION METHODS

Russian Journal of Economics and Law, 2011
For the companies that manufacture medical cork, one of the key elements of effective action is the optimal management of production program. Specificity of planning the production program of these enterprises, which is associated with both internal and ...
A. A. Kushner
doaj  

Annual Grass Silage: A Productive and Cost-Effective Strategy for Ruminant Nutrition

Advances in Agriculture
This study was conducted to evaluate the agronomic performance, fermentation characteristics, cost analysis, and financial returns of silage produced from annual forage crops.
Felipe Pontes Teixeira das Chagas, Ana Beatriz Graciano da Costa, Stela Antas Urbano, Juliana Caroline Santos Santana, Anne Carolinne Rodrigues Linhares da Silva, Patrick Bezerra Fernandes, Kyvia Pontes Teixeira das Chagas, Flávio Pereira da Mota Silveira, João Virgínio Emerenciano Neto   +8 more
doaj   +1 more source