Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Constraint monitoring in TOSCA [PDF]
The Job-Shop Scheduling Problem (JSSP) deals with the allocation of resources over time to factory operations. Allocations are subject to various constraints (e.g., production precedence relationships, factory capacity constraints, and limits on the ...
Beck, Howard
core +1 more source
Creation and implementation of customised production scheduling software in a processed cheese factory : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Manufacturing and Industrial Technology at Massey University [PDF]
, 2000 This project investigated creating computer algorithms and friendly software interfaces to assist with the scheduling of single stage operations with sequence dependant set-ups and crew rostering problems across multiple lines.
Aitken, Ross
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Large-Scale Customized Production Scheduling of Multiagent-Based Medical 3D Printing. [PDF]
Comput Intell Neurosci, 2022 He J, Wu J, Zhang Y, Wang Y, He H.
europepmc +1 more source
HEURISTIC AND OPTIMUM SOLUTIONS IN ALLOCATION PROBLEMS [PDF]
In this paper we present some models and algoritms for solving some typical production planning and scheduling problems. We present the Resource-Constrained Project Scheduling Problem (RCPSP) and algorithms for the determination of maximal couplings with
Iulian Mircea, Radu R. Şerban
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Revista Científica de Ingeniería Industrial, 2014 RESUMEN El propósito de esta investigación fue diseñar la programación óptima de la producción en una pequeña empresa de calzado ubicada en la ciudad de San José de Cúcuta (Colombia), donde se identificaron las restricciones del sistema productivo ...
Viviana Karolina Ortiz-Triana
doaj
IEEE AccessWith the transformation of manufacturing towards intelligence and flexibility, the workshop scheduling problem, as a typical combinatorial optimization problem, is facing increasingly complex constraints and requirements. In the actual production process,
Tingting Qu
doaj +1 more source
Application of Blockchain Technology in Production Scheduling and Management of Human Resources Competencies. [PDF]
Sensors (Basel), 2022 Balon B, Kalinowski K, Paprocka I.
europepmc +1 more source