Results 91 to 100 of about 14,109,241 (348)

The Impact of Downtime on the Stability of the Production Schedule

Applied Sciences
Production scheduling is a fundamental element for the efficient control of material flow in production processes. Research work concerns the approaches, methods and tools used to optimize the loading of production resources with production orders ...
Piotr Kaźmierczak, Krzysztof Żywicki, Paulina Rewers   +2 more
doaj   +1 more source

Flexible job-shop scheduling based on genetic algorithm and simulation validation

MATEC Web of Conferences, 2017
This paper selects flexible job-shop scheduling problem as the research object, and Constructs mathematical model aimed at minimizing the maximum makespan.
Zhou Erming, Zhu Jin, Deng Ling
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A branch-and-bound algorithm for stable scheduling in single-machine production systems. [PDF]

Robust scheduling aims at the construction of a schedule that is protected against uncertain events. A stable schedule is a robust schedule that will change little when variations in the input parameters arise.
Herroelen, Willy, Leus, Roel
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Involvement of Various Selection Methods for Genetic Algorithms in Determining the Optimal Production Schedule Problem

JOIV: International Journal on Informatics Visualization
This research investigates using genetic algorithms (GA) to optimize production scheduling in Medan's shoe industry. The study compares traditional manual and First Come First Serve (FCFS) methods against a GA approach, incorporating selection variations
Rizki Muliono, Nukhe Andri Silviana, Nanda Novita   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The impact of predictive inaccuracies on execution scheduling [PDF]

, 2004
This paper investigates the underlying impact of predictive inaccuracies on execution scheduling, with particular reference to execution time predictions. This study is conducted from two perspectives: from that of job selection and from that of resource
Nudd, G. R., Stephen A. Jarvis, Nudd, Graham R., Jarvis, Stephen A.; id_orcid, He, Ligang, Daniel P. Spooner, Spooner, Daniel P., Ligang He, Jarvis, Stephen A., Graham R. Nudd   +9 more
core   +1 more source

Exact and Heuristic Approaches for Weighted Throughput Maximization in Single-Machine Scheduling

Mathematics
This study investigates a single-machine throughput maximization problem (TMP), in which each job is characterized by a processing time, ready date, due date, and weight, and must be completed within its time window to yield profit.
Yi-Feng Hung, Jia-Shain Lin, Chih-Hao Lai, Chia-Hui Chien   +3 more
doaj   +1 more source

Integrating Preventive Maintenance Scheduling As Probability Machine Failure And Batch Production Scheduling

ComTech, 2016
This paper discusses integrated model of batch production scheduling and machine maintenance scheduling. Batch production scheduling uses minimize total actual flow time criteria and machine maintenance scheduling uses the probability of machine failure
Zahedi Zahedi, Ashadi Salim
doaj   +1 more source