Results 81 to 90 of about 30,048 (219)

Modeling and optimization of bakery production scheduling to minimize makespan and oven idle time. [PDF]

Sci Rep, 2023
Babor M, Paquet-Durand O, Kohlus R, Hitzmann B.   +3 more
europepmc   +1 more source

Programación óptima de la producción en una pequeña empresa de calzado – en Colombia / Optimal production scheduling in a small shoe business in Colombia

Revista Científica de Ingeniería Industrial, 2014
RESUMEN El propósito de esta investigación fue diseñar la programación óptima de la producción en una pequeña empresa de calzado ubicada en la ciudad de San José de Cúcuta (Colombia), donde se identificaron las restricciones del sistema productivo ...
Viviana Karolina Ortiz-Triana
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Enumeration optimization of open pit production scheduling based on mobile capacity search domain. [PDF]

Sci Rep, 2023
Xu X, Gu X, Wang Q, Zhao Y, Kong W, Zhu Z, Wang F.   +6 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Large-Scale Customized Production Scheduling of Multiagent-Based Medical 3D Printing. [PDF]

Comput Intell Neurosci, 2022
He J, Wu J, Zhang Y, Wang Y, He H.
europepmc   +1 more source

Algorithm for Solving Distributed Workshop Scheduling Model Based on Order Constraints and Assembly Constraints

IEEE Access
With the transformation of manufacturing towards intelligence and flexibility, the workshop scheduling problem, as a typical combinatorial optimization problem, is facing increasingly complex constraints and requirements. In the actual production process,
Tingting Qu
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Application of Blockchain Technology in Production Scheduling and Management of Human Resources Competencies. [PDF]

Sensors (Basel), 2022
Balon B, Kalinowski K, Paprocka I.
europepmc   +1 more source