Results 61 to 70 of about 375,167 (310)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Synthesis and Stochastic Assessment of Cost-Optimal Schedules [PDF]

, 2006
We present a novel approach to synthesize good schedules for a class of scheduling problems that is slightly more general than the scheduling problem FJm,a|gpr,r_j,d_j|early/tardy.
Bohnenkamp, H.C., Hermanns, H., Hurink, J.L., Jansen, D.N., Mader, A.H., Usenko, Y.S.   +5 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Real-Time Production Scheduling and Industrial Sonar and Their Application in Autonomous Mobile Robots

Applied Sciences
In real-time production planning, there are exceptional events that can cause problems and deviations in the production schedule. These circumstances can be solved with real-time production planning, which is able to quickly reschedule the operations at ...
Francisco Burillo, María-Pilar Lambán, Jesús-Antonio Royo, Paula Morella, Juan-Carlos Sánchez   +4 more
doaj   +1 more source

SCHEDULING INPUTS WITH PRODUCTION FUNCTIONS: OPTIMAL NITROGEN PROGRAMS FOR RICE [PDF]

The problem of scheduling input applications can be examined by extending conventional production function analysis. Using appropriately designed agricultural experiments, it is possible to estimate production function parameters with alternative ...
Griffin, Ronald C., Montgomery, John M., Rister, M. Edward, Turner, Fred T.   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluation of scheduling techniques for payload activity planning [PDF]

Two tasks related to payload activity planning and scheduling were performed. The first task involved making a comparison of space mission activity scheduling problems with production scheduling problems.
Bullington, Stanley F.
core   +1 more source

Production/maintenance cooperative scheduling using multi-agents and fuzzy logic [PDF]

, 2002
Within companies, production is directly concerned with the manufacturing schedule, but other services like sales, maintenance, purchasing or workforce management should also have an influence on this schedule.
AYEL J., B. Archimède, B. Grabot, BARNETT K. W., BASKER B. A., DENIAUD S., Fox M. S., HAMMER M., ISHII H., MIYASHITA K., PARUNAK H. V. D., PATE-CORNELL M. E., SAAD A., SHEN W., SMITH S. F., T. Coudert   +15 more
core   +5 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Amendment of Heuts-Selen's lotsizing and sequencing heuristic for single stage process manufacturing systems [PDF]

Productivity;Production Scheduling;Manufacturing ...
Ashayeri, J., Esch, W.H.L. van, Heuts, R.M.J.   +2 more
core   +1 more source