Results 91 to 100 of about 11,185,446 (211)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
ALLOCATABLE FIXED INPUTS AND JOINTNESS IN AGRICULTURAL PRODUCTION: MORE IMPLICATIONS [PDF]
The presence of allocatable fixed inputs may cause truly joint technologies to appear nonjoint in the short run as well as truly nonjoint technologies to appear joint.
Shumway, C. Richard, Asunka, Samuel
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Technologies for African Agricultural Transformation (TAAT) Program was initiated by the African Development Bank (AfDB) as part of its Feed Africa Initiative.
Technologies for African Agricultural Transformation
core +1 more source
The review deals with the baroreflex regulation of circulation in chronic heart failure (CHF). The pathophysiological aspects of development of dysfunction of the baroreflex clinically estimated from its sensitivity are presented; the clinical value of ...
Mikhail Viktorovich Nepoklonov +9 more
doaj
Wavelet Decomposition of Close-to-Process Acceleration Signals for Wear Monitoring
Highly automated and unmanned manufacturing requires process monitoring and in-process control to prevent damage to the workpiece or machine tool due to tool failure.
Julian-Amon Greitler +2 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Nonparametric estimation of concave production technologies by entropic methods [PDF]
An econometric methodology is developed for nonparametric estimation of concave production technologies. The methodology, bases on the priciple of maximum likelihood, uses entropic distance and concvex programming techniques to estimate production ...
Alex Shapiro +4 more
core
Flexible manufacturing application integration (MAI) in photovoltaic production environments
27 S.This presentation discusses the effective use of a Service Oriented Architecture (SOA) in production environments from ERP, MES down to equipments and introduces advantages of using Manufacturing Application Integration (MAI) especially in ...
Dreiss, P.
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

