Results 151 to 160 of about 14,992,974 (297)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Information Technology Newsletter July 2005

open access: yes, 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter July 2005.
University of Minnesota: Office of Information Technology
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Information Technology Newsletter June 2005

open access: yes, 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter June 2005.
University of Minnesota: Office of Information Technology
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Information Technology Newsletter December 2004

open access: yes, 2004
University of Minnesota: Office of Information Technology. (2004). Information Technology Newsletter December 2004.
University of Minnesota: Office of Information Technology
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

The Impact of Production Technology on the Quality of Potato Spirit. [PDF]

open access: yesMolecules
Balcerek M   +4 more
europepmc   +1 more source

Information Technology Newsletter April 2005

open access: yes, 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter April 2005.
University of Minnesota: Office of Information Technology
core  

Home - About - Disclaimer - Privacy