Results 141 to 150 of about 1,894,927 (308)

Research of large chemical production line simulation technology

open access: yes, 2016
The aim of simulation technique for production line is to find out the most feasible scheme which designers made for the project. Simulation technique can verify the actual effect of the project from the schemes. Combined with the actual production mode,
Bai XL(白鑫林)   +4 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Potential impact of groundnut production technology on welfare of smallholder farmers in Ghana. [PDF]

open access: yesPLoS One, 2022
Kotu BH   +4 more
europepmc   +1 more source

Inventing modern production technology for human-centric music performance

open access: yes, 2020
Thesis: Ph. D., Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, February, 2020Cataloged from student-submitted PDF of thesis.Includes bibliographical references (pages 277-285).Fifty-two ...
Bloomberg, Benjamin Arthur Philips.
core  

Production system improvement : floor area reduction and visual management [PDF]

open access: yes, 2012
Thesis (M. Eng. in Manufacturing)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Chen, Zhuling, M. Eng. Massachusetts Institute of Technology
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Effect of Production Technology Intensity on the Grain Yield, Protein Content and Amino Acid Profile in Common and Durum Wheat Grain. [PDF]

open access: yesPlants (Basel), 2023
Sułek A   +7 more
europepmc   +1 more source

Adoption of Technology, Management Practices, and Production Systems in U.S. Milk Production

open access: yes
We examine U.S. dairy farmer adopter characteristics and adoption rates of eleven technologies. Excepting grazing, technologies were generally adopted complementarily. Four were used on higher percentages of farms in 2005 than 2000.
MacDonald, James M.   +2 more
core  

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