Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Commercially Available Enteric Empty Hard Capsules, Production Technology and Application. [PDF]
Pharmaceuticals (Basel), 2022 Franc A, Vetchý D, Fülöpová N.
europepmc +1 more source
Endogenous Technology Adoption Under Production Risk: Theory and Application to Irrigation Technology [PDF]
The main objective of this paper is to present a theoretical framework that conceptualizes technology adoption as a decision process involving information acquisition by farmers who face yield uncertainty and vary in their risk preferences.
Celine Nauges +2 more
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Chemistry and Production Technology of Hallstatt Period Glass Beads from Bohemia. [PDF]
Materials (Basel), 2022 Zlámalová Cílová Z +3 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Sports resources utilization efficiency, productivity change, and regional production technology heterogeneity in Chinese Provinces: DEA-SBM and Malmquist Index Approaches. [PDF]
PLoS One, 2023 Zhang H, Shi Y, Jiang X, Xu X, Shah WUH.
europepmc +1 more source
Production Under Uncertainty: A Simulation Study [PDF]
In this article we model production technology in a state-contingent framework. Our model analyzes production under uncertainty without regard to the nature of producer risk preferences. In our model producers?
C.J. O’Donnell +2 more
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
An Intelligent Music Production Technology Based on Generation Confrontation Mechanism. [PDF]
Comput Intell Neurosci, 2022 Li Y, Liu X.
europepmc +1 more source