Results 121 to 130 of about 14,992,974 (297)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Commercially Available Enteric Empty Hard Capsules, Production Technology and Application. [PDF]
Pharmaceuticals (Basel), 2022 Franc A, Vetchý D, Fülöpová N.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
RETRACTED: Sports resources utilization efficiency, productivity change, and regional production technology heterogeneity in Chinese Provinces: DEA-SBM and Malmquist Index Approaches. [PDF]
PLoS One, 2023 Zhang H, Shi Y, Jiang X, Xu X, Shah WUH.
europepmc +1 more source
The object of research is the process of the maintenance used in the HAMMA BOUZIENE cement factory (Algeria), where an attempt was made to devolope a new maintenance policy based on preventive maintenance instead of corrective maintenance.
Khammar, Leila +2 more
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Chemistry and Production Technology of Hallstatt Period Glass Beads from Bohemia. [PDF]
Materials (Basel), 2022 Zlámalová Cílová Z +3 more
europepmc +1 more source
Further Model-Based Estimates of U.S. Total Manufacturing Production Capital and Technology, 1949-2005 [PDF]
Production capital and technology (i.e., total factor productivity) in U.S. manufacturing are fundamental for understanding output and productivity growth of the U.S.
Peter A. Zadrozny, Baoline Chen
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
An Intelligent Music Production Technology Based on Generation Confrontation Mechanism. [PDF]
Comput Intell Neurosci, 2022 Li Y, Liu X.
europepmc +1 more source