Results 111 to 120 of about 17,071,436 (301)

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

DEVELOPMENT OF A NEW SAUSAGE PRODUCT USING NATURAL ADDITIVES OF PLANT ORIGIN

open access: yesШәкәрім университетінің хабаршысы: Техника ғылымдар
The article is devoted to the prospects of using natural vegetable raw materials as food additives in the meat processing industry using the example of a new sausage product.The need to create such products arose as a result of the current situation with
D. Sviderskaya   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Framework for feminist technology intervention [PDF]

open access: yes, 2008
Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2008.Includes bibliographical references (p. 58-60).This thesis describes a feminist framework for technological interventions.
Rüst, Annina Julia
core  

THE TECHNOLOGY OF YOGURT PRODUCTION WITH BIOLOGICALLY ACTIVE PLANT-BASED ADDITIVES

open access: yesШәкәрім университетінің хабаршысы: Техника ғылымдар
This article discusses modern methods of producing yogurts with the addition of plant-based biologically active additives. The article describes the main components used to enrich yogurts with plant extracts, their impact on the organoleptic and ...
A. Bepeyeva   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Innovative approaches to integrating gender into conventional maize breeding: lessons from the Seed Production Technology for Africa project. [PDF]

open access: yesFront Sociol, 2023
Voss RC   +10 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Adoption of Technology, Management Practices, and Production Systems in U.S. Milk Production [PDF]

open access: yes
We examine U.S. dairy farmer adopter characteristics and adoption rates of eleven technologies. Excepting grazing, technologies were generally adopted complementarily. Four were used on higher percentages of farms in 2005 than 2000.
MacDonald, James M.   +2 more
core  

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