Results 101 to 110 of about 1,894,927 (308)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Sustainability of production and marketing practices in hog raising: Philippine context

open access: yesInternational Journal of Academe and Industry Research
This qualitative study employed a descriptive phenomenological research design to explore the production technology and hog marketing strategies among hog raisers in selected municipalities of Quezon Province, Philippines. Twelve participants, comprising
Rustom B. Obrador, Randall B. Pasco
doaj   +1 more source

COLLABORATIVE STRATEGIES FOR SUCCESSFUL PRODUCTION TECHNOLOGY DEVELOPMENT PROJECTS

open access: yes, 2014
Collaborative development between the user and the equipment supplier of production technology has an increasingly important effect in terms of generating innovative, sustainable, and unique production process ideas that can be easily ramped-up to high ...
Bruch, Jessica,   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Further Model-Based Estimates of U.S. Total Manufacturing Production Capital and Technology, 1949-2005 [PDF]

open access: yes
Production capital and technology (i.e., total factor productivity) in U.S. manufacturing are fundamental for understanding output and productivity growth of the U.S.
Peter A. Zadrozny, Baoline Chen
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Determinants of Growth Rate of Industrial Production in Iran (1996-2011) [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2014
Industries are  one of the most important economic sectors and their growth causes industrial and economical development.There are some important and effective factors which imporve the industrial production growth and the value added of enterprises ...
Mohammad Mowlaei, Razieh Sahrai
doaj  

Foam polystyrene production technology.

open access: yes, 2016
The aim of polystyrene plant and describe their technology. To describe the entire production technology, select the necessary facilities. To create the soak time schedule. Solutions. Designed bungalows styrofoam factory, a length of 24,40 m, width 18.40
Pečiulis, Danielius,
core  

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