Results 101 to 110 of about 5,191,690 (310)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Study on Production Technology and Volatile Flavor Analysis of Fragrance Zanthoxylum Seasoning Oil. [PDF]

Foods, 2023
Li H, Sun J, He X, Zhang C, Liao Z, Li D, Wang H.   +6 more
europepmc   +1 more source

Technical efficiency and technology gaps in beef cattle production systems in Kenya: A stochastic metafrontier analysis [PDF]

In this study the stochastic metafrontier method is used to investigate technical efficiency and technology gaps across three main beef cattle production systems in Kenya.
Hubbard, Lionel J., Otieno, David Jakinda, Ruto, Eric   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Sustainability of production and marketing practices in hog raising: Philippine context

International Journal of Academe and Industry Research
This qualitative study employed a descriptive phenomenological research design to explore the production technology and hog marketing strategies among hog raisers in selected municipalities of Quezon Province, Philippines. Twelve participants, comprising
Rustom B. Obrador, Randall B. Pasco
doaj   +1 more source

Fertilizer Production and Technology

, 1959
RESP-17364 631.82 ...
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Roman Republican coarse ware from Norba, Southern Lazio (Italy): a multi-analytical study of production technology and trade. [PDF]

Archaeol Anthropol Sci, 2023
Borgers B, Ionescu C, Gál Á, De Haas T, Barbu-Tudoran L.   +4 more
europepmc   +1 more source

REAL OPTIONS ANALYSIS FOR INVESTMENT IN ORGANIC WHEAT AND BARLEY PRODUCTION IN SOUTH CENTRAL NORTH DAKOTA USING PRECISION AGRICULTURE TECHNOLOGY [PDF]

Real options theory is employed to measure the value of investing in organic wheat production using precision agriculture technology. Results reveal that an option to wait until market uncertainty is resolved is valuable.
Boehlje, Michael, Ehmke, Mariah D., Golub, Alla A., Harbor, Anetra L.   +3 more
core   +1 more source