Results 91 to 100 of about 5,191,690 (310)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Research Progress on Replacement and Production Technology for Long-Distance Liquefied Ethane Pipelines. [PDF]

ACS Omega, 2023
Ban J, Yuan X, Li C, Zhang W, Tang Y, Yang W.   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Influence of Production Technology Intensity on the Yield and Amino Acid Profile of the Grain Protein of Different Sowing Oat (Avena sativa L.) Cultivars

Agronomy
The biological value of protein is mainly determined by its amino acid composition, and primarily depends on the optimal content of individual exogenous amino acids.
Alicja Sułek, Grażyna Cacak-Pietrzak, Marcin Różewicz, Anna Nieróbca, Marcin Studnicki, Grażyna Podolska   +5 more
doaj   +1 more source

Further Model-Based Estimates of U.S. Total Manufacturing Production Capital and Technology, 1949-2005 [PDF]

Production capital and technology (i.e., total factor productivity) in U.S. manufacturing are fundamental for understanding output and productivity growth of the U.S.
Baoline Chen, Peter A. Zadrozny
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pelatihan Penerapan Teknologi Alat Produksi dan Pengemasan bagi UMKM Labuana Kota Banjarbaru Kalimantan Selatan

Jurnal Pengabdian UNDIKMA
This community service aims to improve the skills of UMKM Labuana in applying production equipment technology and product packaging instruments. The methods used include initial surveys, followed by technology application training, and evaluation with ...
Normaidah Normaidah, Muhammad Itqan Mazdadi, Prima Happy Ratnapuri, Putri Helena Junjung Buih   +3 more
doaj   +1 more source

Research Progress of Hydrogen Production Technology and Related Catalysts by Electrolysis of Water. [PDF]

Molecules, 2023
Li H, Guo J, Li Z, Wang J.
europepmc   +1 more source

Choice of Flexible Production Technologies Under Strategic Delegation [PDF]

This work analyzes a managerial delegation model in which firms can choose between a flexible production technology which allows them to produce two different products and a dedicated production technology which limits production to only one product.
Bárcena Ruiz, Juan Carlos, Olaizola Ortega, María Norma   +1 more
core