A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Amulets Depicting the Eye of Horus from Burial Mounds of Early Nomads in the Southern Urals
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2018 Three faience amulets depicting the Eye of Horus (Wedjat) were discovered in the Southern Urals. They all come from burial mounds of early nomads and are dated by local chronologies to the 5th – 4th centuries BC.
Olga V. Anikeeva, [Leonid T. Yablonsky]
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Self-evolving online collaborative production model for social enterprise grassroots startups [PDF]
, 2013 Thesis (S.M. in Architecture Studies)--Massachusetts Institute of Technology, Dept. of Architecture, 2013.Cataloged from PDF version of thesis. Vita. Page 118 blank.Includes bibliographical references (pages 109-117).Collaborative production is a process
Gao, Yu, S.M. Massachusetts Institute of Technology
core
Research Progress on Replacement and Production Technology for Long-Distance Liquefied Ethane Pipelines. [PDF]
ACS Omega, 2023 Ban J +5 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Weaponry of the upper Taz River Selkups according to metallographic studies (based on materials from the Kikki-Akki burial ground) [PDF]
Вестник археологии, антропологии и этнографииThe paper presents the analysis of the weaponry items (108 arrowheads, 2 spearheads, and 2 glaive heads) recovered from the 17th–19th cc. burial ground of Kikki-Akki (Yamalo-Nenets Autonomous Okrug, Taz River) of the Upper Taz Selkups, aiming at the ...
Zinyakov N.M., Poshekhonova O.E.
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inventing modern production technology for human-centric music performance
, 2020 Thesis: Ph. D., Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, February, 2020Cataloged from student-submitted PDF of thesis.Includes bibliographical references (pages 277-285).Fifty-two ...
Bloomberg, Benjamin Arthur Philips.
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Research Progress of Hydrogen Production Technology and Related Catalysts by Electrolysis of Water. [PDF]
Molecules, 2023 Li H, Guo J, Li Z, Wang J.
europepmc +1 more source