Results 71 to 80 of about 5,191,690 (310)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
CerâmicaSeventeen ceramics samples (515±95 BP, about 580 years old) and two clay raw materials from Zamala (Far-northern, Cameroon) were characterized by X-ray diffraction (XRD), thermal analysis (DTA/TG) and X-ray fluorescence spectroscopy.
Z. L. Epossi Ntah +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Belarusian Scientific School “Gears”
Механика машин, механизмов и материаловInformation is presented on Belarusian scientific school “Gears” (I.S. Tsitovich, O.V. Berestnev, V.B. Algin, V.E. Antonyuk etc.) from the moment of its origin in 1973 at the Joint Institute of Mechanical Engineering of the NAS of Belarus (at that time –
Victor E. Starzhinsky +2 more
doaj +1 more source
Multi-criteria optimization of properties of non-woven construction thermal insulation from wool fiber [PDF]
Нанотехнологии в строительствеIntroduction. Currently, there are urgent issues of providing production facilities with domestic materials that are not inferior in quality to imported analogues. Materials for construction, including thermal insulation materials, are required for the
Konstantin E. Razumeev +3 more
doaj +1 more source
International production, technology diffusion, and trade [PDF]
The paper develops a general equilibrium model of international production and trade. Technology is carried across borders by multinational producers and the set of technologies being used in a particular country is endogenous.
Shikher, Serge
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 Introduction. Due to the growth of general surgical diseases, the treatment and cessation of bleeding is an important problem of medicine and pharmacy.
Yu. N. Barsukova, O. A. Melnikova
doaj +1 more source
Technology, Information Production, and Market Efficiency [PDF]
A well functioning securities market relies on the availability of accurate information, a broad base of investors who can process this information, legal protection of these investors’ rights, and a liquid secondary market unencumbered by excessive ...
Andrei Shleifer +2 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source