Results 51 to 60 of about 17,071,436 (301)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Jurnal Pengabdian UNDIKMAThis community service aims to improve the skills of UMKM Labuana in applying production equipment technology and product packaging instruments. The methods used include initial surveys, followed by technology application training, and evaluation with ...
Normaidah Normaidah +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Production system improvement : floor area reduction and visual management [PDF]
, 2012 Thesis (M. Eng. in Manufacturing)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Chen, Zhuling, M. Eng. Massachusetts Institute of Technology
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Recent development of ductile cast iron production technology in China [PDF]
China Foundry, 2008 Recent progress in the production and technology of ductile cast iron castings in China is reviewed. The manufacture and process control of as-cast ductile iron are discussed.
Cai Qizhou, Wei Bokang
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
AgronomyThe biological value of protein is mainly determined by its amino acid composition, and primarily depends on the optimal content of individual exogenous amino acids.
Alicja Sułek +5 more
doaj +1 more source
Analysis of state and application of technological process to pheasant farm by regional hunting association in Serbia [PDF]
Agroznanje, 2011 The Hunting Association of Serbia over its 212 regional hunting associations, managed with 89% of the total area of hunting grounds in Serbia. Twenty-two regional hunting associations are registered pheasant production, and is now manufacturing process ...
Popović Zoran +4 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source