Results 41 to 50 of about 5,191,690 (310)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Theoretical assumptions in development the undergroud facilities in different geomechanical conditions [PDF]

open access: yesMining and Metallurgy Engineering Bor, 2015
The aim of this paper is to achieve a rational rates in development the underground facilities at the lowest costs of construction and possible maximum quality (in this case, under the quality is implied the satisfactory stability of contour of developed
Milentijević Gordana   +1 more
doaj   +1 more source

A comprehensive review of the production technology of Cannabis sativa L. with its current legal status and botanical features

open access: yesFundamental and Applied Agriculture, 2023
Cannabis sativus L. is an annual, deciduous, dimorphic, flowering plant that is distributed all over the world. Despite its tremendous and handy usage in medicinal and other areas, the cultivation, production, and trade of cannabis are illegal in most of
Shubh Pravat Singh Yadav   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Planting position and application of different doses of nitrogen at different times on cassava

open access: yesCiência e Agrotecnologia, 2022
In this study, we evaluated the impact of two planting positions of cassava cuttings, cv. ‘Vassourinha’, combined with different times and doses of nitrogen application, on productivity and other agronomic traits.
Jorge González Aguilera   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

SCIENTIFIC AND ARCHAEOLOGICAL STUDY OF PURPLE OCTAGONAL CYLINDRICAL ITEM EXCAVATED FROM THE HEJIA CEMETERY, XIANYANG, SHAANXI, CHINA AND THE ISSUES RELATED TO IT

open access: yesТеория и практика археологических исследований, 2023
In this paper, we chose late war purple octagonal prismatic ware excavated at the Hejia Cemetery in Xianyang as the object of study, and carried out scientific analysis using ultra-deep field microscopy, scanning electron microscopy and energy spectrum ...
Ф. Сунь
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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