Results 81 to 90 of about 5,191,690 (310)
Quality of Knowledge Technology, Returns to Production Technology and Economic Development [PDF]
Presenting a discrete time version of the Romer (1986) model, this paper analyzes optimal paths in a one-sector growth model when the technology is not convex.
Cuong LE VAN, H. Cagri SAGLAM
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Chemical production on Mars using in situ propellant production technology [PDF]
In situ propellant production (ISPP) was examined in terms of its applicability to a manned Mars mission. Production of oxygen from Martian atmosphere was used as the baseline system for ISPP technology assessment.
Ash, Robert L.
core +1 more source
Research, development and application of the innovational technology of high quality pump-compressor pipes production from sections [PDF]
, 2013 The innovational technology of high-strength, cold- and corrosion-resistant pump-compressor pipes from sections was developed. It includes the reduction process inside three-high stand of screw rolling before piercing in the «80» pipe-rolling mill line ...
Bogatov, A. A. +2 more
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The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]
, 2019 Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir +5 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Competitiveness of Kenyan and Ugandan Maize Production: Challenges for the Future [PDF]
The purpose of this study is to assess the costs of maize production in Kenya and Uganda, starting from the fact that there is no single “cost of production” for maize.
Jayne, Thomas S. +2 more
core +1 more source
Possible versus desirable in instructional systems: Who's driving? [PDF]
, 1998 This paper takes a pragmatic stance that the key to successful application of technology in education is good teaching: using technology only when it is a cost‐effective servant of pedagogy.
Carswell, Linda
core +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source