Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Système d'élevage et économie de la production caprine dans les zones traditionnelles du Zimbabwe. I. Les bâtiments d'élevage [PDF]
Dans le cadre de l'enquête nationale sur "la mortalité des chevreaux dans les zones communales du Zimbabwe", les caractéristiques de 219 bâtiments d'élevage, utilisés par les petits ruminants, ont été enregistrées et analysées.
Borne, Pierre Marie +2 more
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
La viande de volaille et les œufs sont des sources principales de protéines animales pour l'alimentation humaine dans le monde. Leur production a augmenté rapidement au cours des dernières décennies.
A. Collin +10 more
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Evaluation du projet Mbarara Goat Farming Association Ouganda : mission du 18 au 25 février 2004 [PDF]
1. Evaluation du projet caprin (Mbarara Goat Farming Association - MGFA): projet financé par le SCAC de Kampala, le projet caprin vise à diffuser en milieu paysan un cheptel caprin amélioré, issu de l'insémination artificielle (opérateur: Alliance ...
Faye, Bernard
core
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Effets saisonniers sur certains paramètres de la production bovine dans les élevages mixtes de l'Etat de Colima au Mexique [PDF]
Dans le cadre d'un programme de coopération franco-mexicain, les auteurs ont effectué pendant deux ans le suivi de 15 élevages bovins du système mixte dans l'Etat de Colima au Mexique.
Cervantes, Norma P. +2 more
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source

