Results 161 to 170 of about 2,275 (257)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

General corruption scale: development and psychometric properties. [PDF]

BMC Psychol
Modesto JG, Pilati R, Ferraz AS, Sarmet MM, Resende MM, Porto JB, Pereira CR.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Wildland-Urban Interface (WUI) Smoke Yields of Nonmethane Organic Gases from Combustion of Small-Scale Residential Building Surrogates. [PDF]

ACS EST Air
Link MF, Davis AY, Lima NM, Falkenstein-Smith RL, Bryant RA, Cleary TG, Poppendieck D.   +6 more
europepmc   +1 more source

Tres productores de Televisión

, 2010
Para responder más de cerca preguntas como ¿En qué piensa Jaime Baily antes de disparar esos tiros certeros y de origen desconocido, como buen francotirador de un canal de televisión? ¿O en quien se inspira Laura Bozzo para escandalizarse histriónicamente frente a un caso de desgracia social?
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

[Nutrition with a planetary health perspective: Strategies for Primary Health Care]. [PDF]

Aten Primaria
Bellido Izquierdo P, Royo Vidal M, Ramírez Arroyo V, Robles Díez E.   +3 more
europepmc   +1 more source

"El productor creativo: ¿tautología o excepción?"

, 2009
Desde los mismos orígenes de la industria cinematográfica, el trabajo del productor ha abarcado tanto competencias financieras y administrativas como creativas, sin existir –por su propia naturaleza– un obligado predominio en uno u otro sentido. Sólo la evolución de la industria del cine, así como las aptitudes personales de quienes han desempeñado ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Oral keratinocyte-mediated inflammation and epithelial disruption: A narrative review on IRF6 signaling and oral carcinogenic risk. [PDF]

Int J Immunopathol Pharmacol
Osorio-Osorno YA, Parada-Sanchez MT.
europepmc   +1 more source