Results 171 to 180 of about 35,572 (298)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

[Recommendations from an antimicrobial stewardship program on the duration of antibiotic treatment: effectiveness of short-course regimens in the emergency department]. [PDF]

Rev Esp Quimioter
Martínez-de La Cruz P, Sánz-Márquez S, Valverde-Cánovas JF, Hervás-Gómez R, Martín-Segarra O, Vegas-Serrano A, Velasco-Arribas M, Losa-García JE, Moreno-Núñez L.   +8 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Preproducción del cortometraje Panóptico: exploración del productor creativo y el cine interactivo [PDF]

Treball de fi de grau – Curs 2023-2024Preproducción del cortometraje Panòptico va començar amb la idea de produir aquest curtmetratge de forma interactiva.
Fernández Ariño, Anaïs
core  

Foliar Traits Drive Chlorophyll Fluorescence Variability in Chilean Sclerophyllous Species Under Early Outplanting Stress. [PDF]

Plants (Basel)
Espinoza S, Magni C, Yáñez M, Toro N, Martínez-Herrera E.   +4 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

When beta-blocker unmasks the diagnosis: pheochromocytoma mimicking acute coronary syndrome. A case report. [PDF]

Arch Peru Cardiol Cir Cardiovasc
Vallejos-Barrientos A, Eslava-Galvez L, García-Gómez I, Angélica-Medrano M, Galvez-Caballero D.   +4 more
europepmc   +1 more source

Formar infants productors de textos

, 1992
Texto en catalán traducido del original francés.
Camps Mundó, Montserrat, Fabrés, Nuria
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Carbon footprint of a clinical biochemistry platform in a French university hospital: Identifying the main greenhouse gas emission sources. [PDF]

J Clim Chang Health
Cécile K, Margaux V, Florence R, Chrystel L, Didier B, Camille CG.   +5 more
europepmc   +1 more source