Results 191 to 200 of about 2,275 (257)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Potential of Classifying Cotton Minicard Stickiness through Vis-NIR Spectroscopy as an Analytical Technique with DD-SIMCA as One-Class Classification. [PDF]

ACS Omega
Liu Y.
europepmc   +1 more source

Impact of Side-Chain Polarity and Symmetry on the Structure and Properties of Acyclic Dioxythiophene Polymers. [PDF]

Chem Mater
Rinehart JM, Xu Z, Wang Z, Österholm AM, Flagg LQ, Richter LJ, Snyder CR, Diao Y, Reynolds JR.   +8 more
europepmc   +1 more source

Crisis and uncertainty in global health. [PDF]

Rev Peru Med Exp Salud Publica
Cueto M.
europepmc   +1 more source

Pyrogenic carbon production from fires in China from 1901 to 2020. [PDF]

iScience
Yuan C, Han M, Sun M, Pan B, Zhao Q, Li W.   +5 more
europepmc   +1 more source

[Asymmetries between national articulation and the autonomy of state governments in implementing health technologies to fight COVID-19 in Argentina]. [PDF]

Cad Saude Publica
Hasdeu S, Beliera A, Alvarez J, Sanchez-Viamonte J.   +3 more
europepmc   +1 more source

Spatial and Sequential Topological Analysis of Molecular Dynamics Simulations of IgG1 Fc Domains. [PDF]

J Chem Theory Comput
Kleczynski M, Bergonzo C, Kearsley AJ.
europepmc   +1 more source

Els productors agraris

Revista de Girona, 2009
openaire   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Medicines withdrawn in other countries due to safety problems, between 2014 and 2023, and their permanence in the Argentine market. [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Caffaratti M, Cañás M, Domosbian DE, Giraudo E, González AM, Lorenzo A, Núñez Montoya S, Rocha MT, Traverso ML, Uema S.   +9 more
europepmc   +1 more source