Results 191 to 200 of about 35,572 (298)

Ciudadanos y Productores

open access: yesAtenea (Concepción), 1928
openaire   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Quantification of some soil properties as affected by land use, and its implication for vegetable farm systems [PDF]

open access: yes, 2010
Alliaume, F.   +5 more
core  

[The β Carba® test can quickly determine the carbapenemases in the microbiology laboratory]. [PDF]

open access: yesRev Esp Quimioter
Serrano-Romero JM   +3 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Tres productores de Televisión

open access: yes, 2010
Para responder más de cerca preguntas como ¿En qué piensa Jaime Baily antes de disparar esos tiros certeros y de origen desconocido, como buen francotirador de un canal de televisión? ¿O en quien se inspira Laura Bozzo para escandalizarse histriónicamente frente a un caso de desgracia social?
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

[Nutrition with a planetary health perspective: Strategies for Primary Health Care]. [PDF]

open access: yesAten Primaria
Bellido Izquierdo P   +3 more
europepmc   +1 more source

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