Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Double-carbapenemase-producing Enterobacteriaceae: complete genome sequencing of isolates from hospitals in Paraguay, 2021. [PDF]
Melgarejo Touchet N +14 more
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The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
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[Subjective implications for adult women who underwent an abortion in Argentina following the enactment of Law 27610]. [PDF]
Lenta MM, Longo RG.
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This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Exact hydrodynamic manifolds for the linear Boltzmann BGK equation I: spectral theory. [PDF]
Kogelbauer F, Karlin I.
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ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
[The technological escalation of medical practice and the impacts on the physician's relationship with their work]. [PDF]
Schraiber LB.
europepmc +1 more source
The nuclear basket nucleoporin MLP1 is required to maintain nuclear integrity, and mitotic fidelity in Trypanosoma brucei. [PDF]
Yagoubat A +9 more
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Effects of Astaxanthin as a Feed Additive on Growth Performance, Intestinal Microbiota and Clinical Parameters in Preweaning Female Holstein Calves: A Preliminary Study. [PDF]
Scaglia E +7 more
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