Results 91 to 100 of about 270,049 (304)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
On groups that have normal forms computable in logspace [PDF]
We consider the class of finitely generated groups which have a normal form computable in logspace. We prove that the class of such groups is closed under passing to finite index subgroups, direct products, wreath products, and certain free products and ...
Elston, G, Elder, M, Ostheimer, G
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Minimal Immersions of Kahler manifolds into Euclidean Spaces [PDF]
It is proved here that a minimal isometric immersion of a Kähler-Einstein or homogeneous Kähler-manifold into an Euclidean space must be totally ...
Di Scala, Antonio Jose'
core +1 more source
Modelling the Effects of Ageing Time of Starch on the Enzymatic Activity of Three Amylolytic Enzymes
The effect of increasing ageing time (t) of starch on the activity of three amylolytic enzymes (Termamyl, San Super, and BAN) was investigated.
Nelson P. Guerra +1 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On solving discrete-time periodic Riccati equations [PDF]
Two numerically reliable algorithms to compute the periodic nonnegative definite stabilizing solution ofdiscrete-time periodic Riccati equations are proposed.
A. Varga, Varga, Andras
core +1 more source
Note on the product of n inhomogeneous linear forms
AbstractIt is proved that if K is a convex body in euclidean n-space with volume V(K), and f(x) is the distance function of K, and t > 0 is such that V(tK) = 2n−1, then given any real number a, there exists an integral point x for which either (i) f(x + a) ⩾ t, or (ii) f(x) ⩾ t and x 0. Several conclusions are drawn. For example, if Li(x), i = 1, 2, 3
openaire +2 more sources

