Results 11 to 20 of about 373,312 (231)

Effective therapeutic targeting of CTNNB1-mutant hepatoblastoma with WNTinib. [PDF]

Mol Oncol
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Balaseviciute U, Huguet-Pradell J, Abril-Fornaguera J, Gris-Oliver A, Rialdi A, Fernández-Martínez E, Montironi C, Del Pozo V, Houghton P, Zanatto L, Mesropian A, Keraite I, Thung S, Armengol C, Sancho-Bru P, Guccione E, Pinyol R, Llovet JM.   +17 more
europepmc   +2 more sources

Occupational balance, quality of life, occupational performance, and disease-related factors in people with multiple sclerosis: A case-control study. [PDF]

Aust Occup Ther J
Abstract Importance Multiple sclerosis is a chronic neurological progressive disease that can lead to different impairments. It may also impact individuals' quality of life and daily living, including occupational performance and occupational balance. However, occupational balance has not been thoroughly described in this population.
Ortiz-Rubio A, Lexell EM, Håkansson C, Navas-Otero A.   +3 more
europepmc   +2 more sources

Dose-Response Association Between Handgrip Strength and All-Cause Mortality Across Different Levels of Systemic Inflammation. [PDF]

J Cachexia Sarcopenia Muscle
ABSTRACT Background Longitudinal associations between C‐reactive protein (CRP) and handgrip strength from cohort studies remain inconsistent. We investigated the dose–response association between handgrip strength and all‐cause mortality across different levels of systemic inflammation.
Tur-Boned A, Andersen LL, López-Bueno R, Núñez-Cortés R, Cruz-Montecinos C, Suso-Martí L, Polo-López A, Calatayud J.   +7 more
europepmc   +2 more sources

Female Starlings With Experimentally Impaired Pre-Laying Condition Produce Smaller But Vitamin A Richer Eggs. [PDF]

J Exp Zool A Ecol Integr Physiol
We experimentally impaired the pre‐laying condition of female starlings by clipping two flight feathers per wing at the beginning of the breeding season, before egg laying. Impaired females laid the same number of eggs as control females, but smaller, and with higher levels of yolk vitamin A.
Casquero S, Redondo I, Gómez-Llanos E, Romero-Haro AÁ, Gil D, Pérez-Rodríguez L.   +5 more
europepmc   +2 more sources

Transcranial Direct Current Stimulation in Parkinson's Disease Patients in the Off State: A Randomized Controlled Crossover Trial Examining the Effects on Pain With and Without the Influence of Dopaminergic Medication. [PDF]

Pain Pract
ABSTRACT Background tDCS has demonstrated hypoalgesic effects on Parkinson's disease (PD)‐related pain applied in the On state but not in the Off state. We aimed to determine the effect of tDCS in the Off state followed by dopaminergic medication on PD‐related pain.
González-Zamorano Y, Moreno-Verdú M, Martínez-Benito A, Fernández-Carnero J, Romero JP.   +4 more
europepmc   +2 more sources

Self-Disassembling Macroporous Metal-Organic Framework-Based Micromotors with Magnetically Controlled Motion for Sequential Drug Release. [PDF]

Small Methods
MOF‐based magnetic micromotors release two drugs in a controlled and sequential manner at the acidic cancer cell media. Abstract Herein, the synthesis of macroporous zeolitic imidazole framework (ZIF)‐based magnetic micromotors (MMs) for the dual encapsulation of 5‐fluorouracil (5‐FU) and doxorubicin (DOX), with pH‐triggered release is described.
Bujalance Fernández J, de la Asunción-Nadal V, Jurado Sánchez B, Escarpa A.   +3 more
europepmc   +2 more sources

Five Years of EVClub-From Journal Club to Worldwide Discussion Hub. [PDF]

J Extracell Vesicles
Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
Alique M, Driedonks TAP, Torrecilhas AC, Witwer KW.   +3 more
europepmc   +2 more sources

Creativity and perceived multiple intelligences as predictors of scholastic aptitude in primary education [PDF]

, 2019
Introducción.  La profundización en constructos como creatividad, inteligencia y aptitudes escolares, y comprender cómo se relacionan entre ellos, puede favorecer un mejor entendimiento de las variables implicadas en el rendimiento académico.
Areces, Débora, Fernández, Estrella, García, Trinidad, Gómez, Cristina, Rodríguez, Celestino   +4 more
core   +2 more sources

Estereotipos de género en universitarios españoles sobre el riesgo psicosocial en la infancia [PDF]

, 2019
Recent studies have shown that gender stereotypes are not sensitive to social changes. There is a gap in how gender is treated in college. This study is part of an innovation project to improve teaching quality in university.
Melero Santos, Sandra, Sánchez Sandoval, Yolanda, Verdugo, Laura, Vizcaya López, Elena   +3 more
core   +4 more sources

Kindness in memorable university teachers [PDF]

, 2017
The article presents some insights derived from research on ‘good teaching practices’ in the context of the School of Humanities, Mar del Plata State University, Argentina.
Flores, Graciela Nelida, Porta Vazquez, Luis Gabriel   +1 more
core   +1 more source