Results 81 to 90 of about 118,934,569 (267)

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source

Platformă bazată pe inteligență artificială pentru dezvoltarea competențelor pe piețele emergente din Balcani

Revista Română de Informatică și Automatică
The growing role of digital platforms in professional development has intensified the need for inclusive, personalised and regionally responsive environments that combine mentorship, networking and lifelong learning.
Monica BARBU, Ioana Cristina VASILOIU, Alina Cristina STĂNESCU   +2 more
doaj   +1 more source

Architectural students' year-out training experience in architectural offices in the UK [PDF]

, 2015
This paper investigates architectural students’ ‘year-out’ learning experience in practices after completing RIBA Part I study within a UK university. By interviewing and analysing their reflections on the experience, the study examines how individual ...
Orr, Kevin, Gao, Yun, Temple, Nicholas, Li, Yan   +3 more
core   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

(A)mending Architecture Education in the Climate Emergency: a focus on values and cultures [PDF]

Research on architecture education in the climate emergency is heavily action focused: while there is a vast body of research around sustainability knowledge and an increasing amount of research on teaching methodology and pedagogy, there is a limited ...
Pelsmakers, Sofie, Kallio, Kirsi Pauliina, Nisonen, Essi   +2 more
core   +1 more source

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

The recontextualisation of architecture and accounting education: Views from the academy and the professions [PDF]

, 2014
This thesis reports on a study of the relationship between practice and higher education. It examines the nature of architecture and accounting professional disciplinary knowledge following the recontextualisation and shift of professional learning into ...
Blickem, Chelsea Jane
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

The role of the business game "Architecture of innovation" in the formation of architect's socio-communicative competence

Вестник Мининского университета
Introduction. The issue of lack of experience in social and professional communication among graduates of architectural schools in the Russian Federation is due to the contradiction between traditional methods of training future architects and constantly
I. V. Topchiy
doaj   +1 more source

THE ROLE OF FOREIGN LANGUAGES IN PREPARING COMPETITIVE PROFESSIONALS IN ARCHITECTURE AND ENGINEERING

This article discusses the critical role of foreign language proficiency, particularly English, in enhancing the competitiveness of architects and engineers in a globalized job market. It explores how language skills support global collaboration by enabling professionals to share and access international knowledge, research, and best practices ...
openaire   +2 more sources