Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang +11 more
wiley +1 more source
NONSPECIFIC VAGINITIS IN PREGNANTS: IS IT POSSIBLE TO TREAT WITH LACTOBACILLUS MAINTENANCE?
Indication of combined medications with wide spectrum of action is more reasonable in treatment of nonspecific vaginitis in pregnants, taking into account frequency of combined infection.
N. V. Spiridonova +2 more
doaj
An Expertise Transfer Framework For Autonomous Surgical Assistance
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao +12 more
wiley +1 more source
To address the problem that existing motion detection models cannot effectively integrate athlete posture and visual information when processing high-speed, highly competitive handball match videos, this paper proposes a multimodal motion detection model
Lu Yan, Yan Si
doaj +1 more source
Integrating knowledge, skills, and attitudes: professional training required for virtual reality therapists in palliative care. [PDF]
Woo OKL.
europepmc +1 more source
Drug Repurposing for Treating NCOR‐Related Intellectual Disability
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong +15 more
wiley +1 more source
Mandibular third molar extraction: perceived surgical difficulty in relation to professional training. [PDF]
Sánchez Jorge MI +7 more
europepmc +1 more source
Enhancing Specific Stiffness of Nano‐Architected Materials Through Generative AI and Active Learning
A structure‐centric generative framework searches voxelated design space directly, coupling a variational autoencoder with multi‐objective optimization and active learning to progressively expand the validated design domain. The discovered nano‐architectures, realized as pyrolytic carbon by two‐photon lithography, deliver 18–23% higher stiffness and 26–
Jinwook Yeo +4 more
wiley +1 more source
Physical Fitness and Psychosocial Profiles of Policewomen from Professional Training Courses and Bodyguard Special Police Sub-Unit. [PDF]
Carrilho M +3 more
europepmc +1 more source
A Biomimetic Solvatochromic Chip With Optimized Chemical Diversity for On‐Site Liquid Identification
A compact biomimetic photonic‐gustatory chip uses Hansen‐solubility‐parameter‐guided solvatochromic disks to create distinct color patterns in organic liquids. An optimized four‐disk array distinguishes solvent types, ratios, homologues, isomers, and alcoholic beverages. Coupled with smartphone imaging and deep learning, it identifies 80 liquid classes
Jintao Zhang +9 more
wiley +1 more source

