Results 211 to 220 of about 388,853 (307)

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

open access: yesAdvanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan   +7 more
wiley   +1 more source

نظرية الإرادة في التربية الصحية assistant Professor associate Professor Professor associate Professor Professor

open access: yes
تهدف التربية الصحية إلى دفع الناس من جميع الاعمار إلى تحمل المسؤولية فيما يتعلق بصحتهم الشخصية. وبهذا فإن الهدف يتمثل في التحلل من انماط السلوك الخطر وبناء انماط سلوك صحي بما في ذلك الاحتفاظ بأنماط السلوك التي تم اكتسابها والتي هي داعمة للصحة. وتتميز هذه العملية بصعوبات كثيرة ولا تحقق على ما يبدو، لدى المعنيين، النجاح المرغوب. فقد ظهر أن كثيرا من انماط
openaire   +1 more source

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

open access: yesAdvanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen   +19 more
wiley   +1 more source

Nível de atividade física dos pais em relação ao Índice de Massa Corporal dos filhos, na escola fundação Bradesco, na cidade Cacoal/RO

open access: yesRevista Brasileira de Obesidade, Nutrição e Emagrecimento, 2012
Maria Silvina Silva Costa   +5 more
doaj  

السلوك الصحي والاتجاهات نحو الصحة assistant Professor associate Professor Professor associate Professor Professor

open access: yes
هدفت هذه الدراسة إلى تحليل السلوك الصحي والاتجاهات الصحية للطّلاب من منظور عبر ثقافي بهدف إيجاد فروق عبر ثقافية بين عينةِ سوريةِ وألمانيةِ. استخدم في الدراسة استبيان السلوك الصحي ، (Steptoe, 1991) الذي يقيس مظاهر معينة من السلوك الصحي والاتجاهات نحوه. اشتملت عينة الدراسة على 300 مفحوص كان بينهم 201 أنثى (67%) و 99 ذكر (33%).
openaire   +1 more source

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

open access: yesAdvanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen   +10 more
wiley   +1 more source

Efeitos fisiológicos do exercício físico combinado com a oclusão vascular parcial: revisão sistemática

open access: yesRevista Brasileira de Prescrição e Fisiologia do Exercício, 2022
João Gabriel Souza Cesar   +3 more
doaj  

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