Results 21 to 30 of about 37,054 (216)
Acta Scientiarum. Education, 2012 Este trabalho tem por finalidade socializar uma pesquisa de cunho bibliográfico que faz parte da dissertação em andamento tecida junto ao Mestrado em Educação: Processos Formativos e Desigualdades Sociais.
Jacqueline de Fatima dos Santos Morais +1 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Algumas velocidades de órbitas planetárias
REMAT, 2019 No presente trabalho são apresentados dados coletados na literatura científica em relação ao afélio e ao periélio de alguns corpos celestes, e com base na primeira lei de Kepler, são determinadas as equações elípticas que descrevem suas trajetórias ao ...
Mylena Marins do Amaral +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
MONITORAMENTO E ESTUDO DE DADOS DO NOVO CORONAVÍRUS NO MUNICÍPIO DE SÃO GONÇALO/RJ.
Ensaios de Geografia, 2020 Desde o começo dos casos de COVID - 19 no Brasil as ações dos governos municipais e estaduais no combate a transmissão do vírus tem sido cada vez mais importante, principalmente atendendo uma perspectiva multi-escalar.
Beatriz Costa de Jesus +2 more
doaj
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source